496808-11-8Relevant articles and documents
Hetero-Diels-Alder additions to pent-4-enofuranosides: Concise synthesis of hydroxylated pyrrolizidines
Gallos, John K,Sarli, Vassiliki C,Stathakis, Christos I,Koftis, Theocharis V,Nachmia, Victoria R,Coutouli-Argyropoulou, Evdoxia
, p. 9351 - 9357 (2002)
A new facile method for the synthesis of hydroxylated pyrrolizidines of the alexine family has been developed, which involves hetero-Diels-Alder addition of ethyl 2-nitrosoacrylate to pent-4-enofuranosides and a further two-step reductive ring opening-ring closure treatment of the cycloadduct.