497107-48-9

Basic information

• Product Name: (2S,3S,5S)-5-Amino-2-dibenzylamino-8-methyl-1-phenyl-nonan-3-ol
• CAS NO: 497107-48-9
• Molecular Weight: 444.66
• Mol File: 497107-48-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S,5S)-5-Amino-2-dibenzylamino-8-methyl-1-phenyl-nonan-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S,5S)-5-Amino-2-dibenzylamino-8-methyl-1-phenyl-nonan-3-ol(497107-48-9)
• EPA Substance Registry System: (2S,3S,5S)-5-Amino-2-dibenzylamino-8-methyl-1-phenyl-nonan-3-ol(497107-48-9)

Safety Data

• Hazardous Substances Data: 497107-48-9(Hazardous Substances Data)

Upstream product

• 4237-74-5 isoamylmagnesium chloride 
• 156732-12-6 (4S)-4-(N,N-dibenzylamino)-3-oxo-5-phenyl-pentanonitrile 
• 111138-83-1 N,N-dibenzyl-L-phenylalanine benzyl ester 

Downstream Products

• 497107-54-7 [(1S,3S,4S)-4-[2-(2,6-Dimethyl-phenoxy)-acetylamino]-3-hydroxy-1-(3-methyl-butyl)-5-phenyl-pentyl]-carbamic acid tert-butyl ester 
• 497107-51-4 [(1S,3S,4S)-4-Amino-3-hydroxy-1-(3-methyl-butyl)-5-phenyl-pentyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

Novel Lopinavir analogues incorporating non-Aromatic P-1 side chains - Synthesis and structure-activity relationships

The HIV protease inhibitor Lopinavir has a pseudosymmetric core unit incorporating benzyl groups at both P-1, P-1′ positions. A series of analogues incorporating non-aromatic side chains at the P-1 position were synthesized and the structure-activity relationships explored.