497239-45-9

Basic information

• Product Name: 3-Oxetanemethanamine, 3-phenyl-
• Synonyms: 3-Oxetanemethanamine, 3-phenyl-;(3-phenyloxetan-3-yl)methanamine;3-phenyl-3-aminomethyloxetane;(3-Phenyloxetan-3-yl)MethylaMine;3-Aminomethyl-3-phenyloxetane;(3-Phenyloxetan-3-yl)
• CAS NO: 497239-45-9
• Molecular Formula: C₁₀H₁₃NO
• Molecular Weight: 163.22
• Mol File: 497239-45-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 273℃
• Flash Point: 124℃
• Appearance: /
• Density: 1.092
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 9.65±0.29(Predicted)
• CAS DataBase Reference: 3-Oxetanemethanamine, 3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Oxetanemethanamine, 3-phenyl-(497239-45-9)
• EPA Substance Registry System: 3-Oxetanemethanamine, 3-phenyl-(497239-45-9)

Safety Data

• Hazardous Substances Data: 497239-45-9(Hazardous Substances Data)

Usage

General Description

3-Oxetanemethanamine, 3-phenyl- is a chemical compound with the molecular formula C9H9NO. It is an organic compound that belongs to the class of oxetanes and amines. This chemical is also known as 3-phenyl-3-oxetane-1-carboxamide and is used in organic synthesis and medicinal chemistry. It is commonly utilized as a building block for the synthesis of various pharmaceuticals and bioactive compounds. 3-Oxetanemethanamine, 3-phenyl- has potential applications in the development of new drugs and has gained attention in the field of research for its pharmacological activities. However, further studies and research are needed to fully understand its properties and potential uses.

Upstream product

• 215719-44-1 (3-phenyl-oxetan-3-yl)methyl p-toluenesulfonate 
• 114012-43-0 (3-phenyl-oxetan-3-yl)methanol 
• 4704-99-8 α,α,α-tris(hydroxymethyl)toluene 
• 215719-41-8 2-(3-phenyloxetan-3-ylmethyl)isoindole-1,3-dione 

Downstream Products

• 497239-46-0 N-(3-phenyloxetan-3-ylmethyl)benzamide 

Relevant articles and documents

Unusual cyclodimerization of small cyclic ethers via neighboring carbonyl-group participation and cation transfer

Oxetanes having both a carbonyl functional group and a phenyl group at the 3-position bring about unusual cyclodimerization under the influence of trifluoromethanesulfonic acid, to give a cis/trans-isomer mixture of substituted 1,3-dioxanes via neighboring carbonyl-group participation, cation transfer including phenonium rearrangement, and cyclodimerization. Oxiranes having a carbonyl functional group also undergo a similar cyclodimerization to form a 1,3-dioxolane ring. No phenyl substituent is required in the cases of the oxiranes, because the cation transfer process involves a 1,2-hydride shift alone. These five- and six-membered cyclic acetals are quite different from ring-expanded cyclic ether dimers expected simply from the back-biting reaction known in the cationic ring-opening polymerization of oxiranes and oxetanes.