49770-81-2Relevant articles and documents
ALICYCLIC MUSK FRAGRANCE COMPOUNDS
-
, (2020/07/14)
The present invention primarily relates to the use of a compound according to the general formula (I) wherein i) m is 1, n is 1, o is 0 or 1, Y is Hydrogen, or ii) m is 2, n is 0, o is 1, Y is methyl, and wherein X is O or methylene, R and R1 are each methyl or form together with the carbon atom attached to a carbonyl group, and R2 is methyl, ethyl, propyl, butyl, butan-2-one-4-yl, tetrahydrofuran-2-yl, or tetrahydrofuran-3-yl, as perfuming ingredients. Moreover, the present invention relates to perfume compositions and perfumed products comprising the before mentioned perfuming ingredients. Still more particularly, the invention relates to a method for producing said perfumed products and a method of imparting and/or increasing musk odor characteristics to perfumed products. This invention also relates to a process for the preparation of said compounds according to the general formula (I).
Cross metathesis of allyl alcohols: How to suppress and how to promote double bond isomerization
Schmidt, Bernd,Hauke, Sylvia
, p. 4194 - 4206 (2013/07/05)
Under standard conditions the cross metathesis of allyl alcohols and methyl acrylate is accompanied by the formation of ketones, resulting from uncontrolled and undesired double bond isomerization. By conducting the CM in the presence of phenol, the catalyst loading and the reaction time required for quantiative conversion can be reduced, and isomerization can be suppressed. On the other hand, consecutive isomerization can be deliberately promoted by evaporating excess methyl acrylate after completing cross metathesis and by adding a base or silane as chemical triggers.
A convenient route to chiral γ-lactones via asymmetric hydrogenation of γ-ketoesters using the RuCl3-BINAP-HCl catalytic system
Starodubtseva, Eugenia V.,Turova, Olga V.,Vinogradov, Maxim G.,Gorshkova, Lilia S.,Ferapontov, Vladimir A.,Struchkova, Marina I.
experimental part, p. 11713 - 11717 (2009/04/11)
A convenient one-step synthesis of chiral γ-lactones has been performed. The method is based on enantioselective hydrogenation of γ-ketoesters using the RuCl3-BINAP-HCl catalytic system. Chiral γ-lactones (91-99% ee) have been isolated in 57-88% yield.
