49775-33-9

Basic information

• Product Name: Hexanedioic acid, 2,2,5,5-tetrachloro-
• CAS NO: 49775-33-9
• Molecular Formula: C6H6Cl4O4
• Molecular Weight: 283.923
• Mol File: 49775-33-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Hexanedioic acid, 2,2,5,5-tetrachloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Hexanedioic acid, 2,2,5,5-tetrachloro-(49775-33-9)
• EPA Substance Registry System: Hexanedioic acid, 2,2,5,5-tetrachloro-(49775-33-9)

Safety Data

• Hazardous Substances Data: 49775-33-9(Hazardous Substances Data)

Upstream product

• 76043-71-5 2,2,5,5-tetrachloror-1,6-hexanedial 
• 96147-14-7 3,3,6,6-tetrachloro-1,2-cyclohexanedione 

Downstream Products

• 102316-25-6 N,N'-Dibenzyl-2,2,5,5-tetrachlor-adipinsaeure-diamidin 

Relevant articles and documents

PRACTICAL SYNTHESIS OF 2,2,5,5-TETRACHLORO-1,6-HEXANEDIOIC ACID, FROM TRANS-1,2-CYCLOHEXANEDIOL OR CYCLOHEXANONE, INVOLVING OXIDATION OF 3,3,6,6-TETRACHLORO-1,2-CYCLOHEXANEDIONE

Trans-1,2-cyclohexanediol was quantitatively converted into 3,3,6,6-tetrachloro-1,2-cyclohexanedione (2) by treatment with chlorine in dimethylformamide.The hydrate of the dione was oxidized by aqueous potassium permanganate to afford the title acid 1 in 91percent overall yield.An alternative low cost preparation was elaborated, providing 2 in 61-74percent yield starting from cyclohexanone in a three step procedure without isolation of intermediates.The reaction seqence involves substitution of α-dichloro- and trichlorocyclohexanones by sodium acetate in acetic acid and chlorination of the resulting 2-hydroxy- and 2-acetoxy-2-cyclohexenones in dimethylformamide.