49800-23-9 Usage
Description
1,2,3,4-Tetrahydro-1-naphthylamine hydrochloride is an organic compound with a chemical structure derived from naphthalene, a type of aromatic hydrocarbon. It is characterized by its unique molecular arrangement and properties, which make it suitable for various applications in different industries.
Uses
Used in Chiral Separation:
1,2,3,4-Tetrahydro-1-naphthylamine hydrochloride is used as a chiral selector for enantiomeric separation in the field of analytical chemistry. Its application is particularly relevant for the separation of enantiomers, which are molecules that are mirror images of each other but are not superimposable. 1,2,3,4-TETRAHYDRO-1-NAPHTHYLAMINE HYDROCHLORIDE aids in distinguishing between these enantiomers, which is crucial in various scientific and industrial processes.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1,2,3,4-tetrahydro-1-naphthylamine hydrochloride is used as an intermediate in the synthesis of various drugs. Its unique chemical properties allow it to be a valuable component in the development of new medications, potentially contributing to the treatment of various medical conditions.
Used in Chemical Research:
1,2,3,4-Tetrahydro-1-naphthylamine hydrochloride is also utilized in chemical research as a reagent or starting material for the synthesis of other complex organic compounds. Its versatility in chemical reactions makes it a valuable tool for scientists and researchers working on the development of new chemical entities and materials.
Used in Enantiomeric Separation with β-Cyclodextrin-Bonded Capillaries:
1,2,3,4-Tetrahydro-1-naphthylamine hydrochloride is used as a chiral selector in enantiomeric separation using β-cyclodextrin-bonded negatively charged polyacrylamide gel-filled capillaries. This application is particularly important in the field of chiral chromatography, where the separation of enantiomers is essential for the analysis and purification of chiral compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 49800-23-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,9,8,0 and 0 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 49800-23:
(7*4)+(6*9)+(5*8)+(4*0)+(3*0)+(2*2)+(1*3)=129
129 % 10 = 9
So 49800-23-9 is a valid CAS Registry Number.
49800-23-9Relevant articles and documents
Synthesis of α-Substituted Primary Benzylamines through Copper-Catalyzed Cross-Dehydrogenative Coupling
Kramer, S?ren
supporting information, p. 65 - 69 (2019/01/04)
A copper-catalyzed route to α-substituted, primary benzylamines by C-H functionalization of alkylarenes is described. The method directly affords the amine hydrochloride salt. Catalyst loadings down to 0.1 mol % in combination with scalability, insensitivity to air and moisture, and no need for column chromatography makes the procedure highly practical. The facile synthesis of the racemate of a blockbuster drug highlights the relevance for the development of pharmaceuticals. Preliminary mechanistic data are also included.
