500055-91-4

Basic information

• Product Name: Benzenepropanoic acid, a-cyano-b-(2-oxopropyl)-, methyl ester
• CAS NO: 500055-91-4
• Molecular Formula: C14H15NO3
• Molecular Weight: 245.278
• Mol File: 500055-91-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenepropanoic acid, a-cyano-b-(2-oxopropyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, a-cyano-b-(2-oxopropyl)-, methyl ester(500055-91-4)
• EPA Substance Registry System: Benzenepropanoic acid, a-cyano-b-(2-oxopropyl)-, methyl ester(500055-91-4)

Safety Data

• Hazardous Substances Data: 500055-91-4(Hazardous Substances Data)

Upstream product

• 122-57-6 1-Phenylbut-1-en-3-one 
• 105-34-0 methyl 2-cyanoacetate 

Downstream Products

• 100727-23-9 2,4-dioxo-6-phenyl-cyclohexanecarbonitrile 
• 109012-81-9 methyl 2-methoxycarbonyl-3-phenyl-5-oxohexanoate 
• 1354642-78-6 methyl 2,5-dioxo-3-phenylhexanoate 
• 952009-31-3 2-methyl-1,4-diphenyl-1H-pyrrole 
• 1373319-70-0 methyl 5-methyl-1,3-diphenyl-1H-pyrrole-2-carboxylate 
• 1373319-64-2 C₁₃H₁₂O₃ 
• 91902-80-6 2-methoxycarbonyl-5-methyl-3-phenylthiophene 

Relevant articles and documents

Facile regiocontrolled three-step synthesis of poly-substituted furans, pyrroles, and thiophenes: Consecutive michael addition of methyl cyanoacetate to α,β-enone, CuI-mediated aerobic oxidation, and acid-catalyzed paal-knorr synthesis

An efficient synthesis of poly-substituted furans, pyrroles, and thiophenes was carried out in a regiocontrolled manner via a three-step process; (i) conjugate addition of methyl cyanoacetate derivatives to α,β-enones, (ii) CuI-mediated aerobic oxidation,

Etude de la reaction de Michael en presence de divers agents complexants des cations alcalins en milieu aprotique ou dans les conditions de transfert de phase

Michael addition of methyl cyanoacetate to benzylideneacetophenone 5a or benzylideneacetone 5b, in THF, under LiOt-Bu or KF catalysis takes place only in the presence of complexing agents for the cation.With LiO.t.Bu, HMPA, diHMPA, NIPA or 12-crown-4 show