500590-62-5Relevant articles and documents
Synthesis, biological evaluation, and structure-activity relationships of novel substituted N-phenyl ureidobenzenesulfonate derivatives blocking cell cycle progression in s-phase and inducing DNA double-strand breaks
Turcotte, Vanessa,Fortin, Sébastien,Vevey, Florence,Coulombe, Yan,Lacroix, Jacques,C?té, Marie-France,Masson, Jean-Yves,C.-Gaudreault, René
experimental part, p. 6194 - 6208 (2012/08/27)
Twenty-eight new substituted N-phenyl ureidobenzenesulfonate (PUB-SO) and 18 N-phenylureidobenzenesulfonamide (PUB-SA) derivatives were prepared. Several PUB-SOs exhibited antiproliferative activity at the micromolar level against the HT-29, M21, and MCF-