500872-37-7Relevant articles and documents
A modular, general and enantiospecific strategy for the synthesis of CVS 1778 analogs: Inhibitors of factor Xa
Organ, Michael G,Xu, Juan,N'Zemba, Blaise
, p. 8177 - 8180 (2007/10/03)
A modular synthetic route has been developed for the synthesis of a series of complex benzalactams which are potent inhibitors of factor Xa. The route produces fused benzalactams of varying ring size via a key-step ring-closing metathesis reaction. The ro