5021-35-2

Basic information

• Product Name: 1-Hydroxy-3,6-bis(2-methylpropyl)pyrazin-2(1H)-one
• Synonyms: 1-Hydroxy-3,6-bis(2-methylpropyl)pyrazin-2(1H)-one;Neoaspergillic acid
• CAS NO: 5021-35-2
• Molecular Formula: C12H20 N2 O2
• Molecular Weight: 224.3
• Mol File: 5021-35-2.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Hydroxy-3,6-bis(2-methylpropyl)pyrazin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Hydroxy-3,6-bis(2-methylpropyl)pyrazin-2(1H)-one(5021-35-2)
• EPA Substance Registry System: 1-Hydroxy-3,6-bis(2-methylpropyl)pyrazin-2(1H)-one(5021-35-2)

Safety Data

• Hazardous Substances Data: 5021-35-2(Hazardous Substances Data)

Relevant articles and documents

New Furanone Derivatives and Alkaloids from the Co-Culture of Marine-Derived Fungi Aspergillus sclerotiorum and Penicillium citrinum

Six new compounds including two furanone derivatives sclerotiorumins A and B (1 and 2), one novel oxadiazin derivative sclerotiorumin C (3), one pyrrole derivative 1-(4-benzyl-1H-pyrrol-3-yl)ethanone (4), and two complexes of neoaspergillic acid aluminiumneohydroxyaspergillin (5) and ferrineohydroxyaspergillin (6) were isolated from the co-culture of marine-derived fungi Aspergillus sclerotiorum and Penicillium citrinum. Compound 3 was the first natural 1,2,4-oxadiazin-6-one. Compound 5 showed significant and selective cytotoxicity against human histiocytic lymphoma U937 cell line (IC50?=?4.2?μm) and strong toxicity towards brine shrimp (LC50?=?6.1?μm), and oppositely increased the growth and biofilm formation of Staphylococcus aureus.