5021-44-3

Basic information

• Product Name: 2-(3-NITROPHENYL)QUINOXALINE
• Synonyms: 2-(3-NITROPHENYL)QUINOXALINE;Quinoxaline, 2-(3-nitrophenyl)-
• CAS NO: 5021-44-3
• Molecular Formula: C₁₄H₉N₃O₂
• Molecular Weight: 251.24
• Mol File: 5021-44-3.mol
• Article Data: 10

Chemical Properties

• Melting Point: 184-185°C
• Boiling Point: 437.3°Cat760mmHg
• Flash Point: 218.3°C
• Appearance: /
• Density: 1.342g/cm³
• Vapor Pressure: 1.94E-07mmHg at 25°C
• Refractive Index: 1.688
• PKA: -0.29±0.30(Predicted)
• CAS DataBase Reference: 2-(3-NITROPHENYL)QUINOXALINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-NITROPHENYL)QUINOXALINE(5021-44-3)
• EPA Substance Registry System: 2-(3-NITROPHENYL)QUINOXALINE(5021-44-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 5021-44-3(Hazardous Substances Data)

Usage

General Description

2-(3-Nitrophenyl)quinoxaline is a chemical compound with the molecular formula C15H9N3O2. It is a yellow crystalline solid that is used in chemical research and drug development. 2-(3-NITROPHENYL)QUINOXALINE is a quinoxaline derivative, which is a heterocyclic compound containing a benzene ring fused to a pyrazine ring. The presence of a nitro group in the 3-position of the phenyl ring makes this compound a potential candidate for various applications, including pharmaceuticals, dyes, and electronic materials. Its unique structure and properties make it a valuable tool for researchers in various scientific disciplines.

InChI:InChI=1/C14H9N3O2/c18-17(19)11-5-3-4-10(8-11)14-9-15-12-6-1-2-7-13(12)16-14/h1-9H

Upstream product

• 6890-77-3 3-nitrophenylglyoxal 
• 95-54-5 1,2-diamino-benzene 
• 2227-64-7 3'-nitro-2-bromoacetophenone 
• 121-89-1 3-Nitroacetophenone 
• 5021-43-2 2-phenylquinoxaline 

Downstream Products

• 1374162-20-5 (S)-2-(3-nitrophenyl)-1,2,3,4-tetrahydroquinoxaline 
• 432004-76-7 3-(quinoxalin-2-yl)benzenamine 

Relevant articles and documents

Silica supported dodecatungstophosphoric acid (DTP/SiO2): An efficient and recyclable heterogeneous catalyst for rapid synthesis of quinoxalines

A facile synthesis of quinoxalines by the cyclocondensation of substituted phenacyl bromides with o-pheneylenediamines using silica-supported dodecatungstophosphoric acid (DTP/SiO2) as a recyclable heterogeneous catalyst is unveiled in this res

Synthesis of quinoxaline using silica supported phosphomolybdic acid as reusable heterogeneous catalyst

Using phosphomolybdic acid on silica as recyclable catalyst we have developed methodology for the synthesis of quinoxalines by condensation of phenacyl bromides and o-phenylene diamines in ClCH2CH2Cl at 80°C. The phosphomolybdic acid

Catalyst-free synthesis of quinoxalines

Quinoxalines are a class of important heterocycles, so to explore a facile and practical new synthetic method is always demanded. We have developed a new catalyst-free domino synthesis of quinoxalines from phenacyl halides and 1,2-diaminoarenes. Phenacyl