5027-63-4 Usage
Description
Saccharolactone, also known as D-glucono-1,4-lactone, is a delta-lactone derived from D-glucono-1,4-lactone with the hydroxy group at position 6 oxidized to the corresponding carboxylic acid. It is a naturally occurring compound with various applications in different industries.
Uses
Used in Pharmaceutical Industry:
Saccharolactone is used as an intermediate in the synthesis of various pharmaceutical compounds, such as antibiotics and other therapeutic agents. Its unique chemical structure allows for the development of new drugs with potential applications in treating various diseases.
Used in Chemical Industry:
In the chemical industry, saccharolactone is utilized as a building block for the production of various organic compounds, including specialty chemicals and additives. Its versatile structure makes it a valuable component in the synthesis of a wide range of products.
Used in Food Industry:
Saccharolactone is employed as a flavor enhancer and a component in the production of certain food additives. Its ability to improve the taste and aroma of various food products makes it a valuable addition to the industry.
Used in Cosmetic Industry:
In the cosmetic industry, saccharolactone is used as an ingredient in the formulation of skincare and personal care products. Its properties contribute to the development of products with improved skin hydration, texture, and overall appearance.
Used in Research and Development:
Saccharolactone is also used in research and development for the study of its chemical properties and potential applications in various fields. Its unique structure and reactivity make it an interesting subject for scientific investigation and the development of new technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 5027-63-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,0,2 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 5027-63:
(6*5)+(5*0)+(4*2)+(3*7)+(2*6)+(1*3)=74
74 % 10 = 4
So 5027-63-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H8O7/c7-1-2(8)6(12)13-4(1)3(9)5(10)11/h1-4,7-9H,(H,10,11)/t1-,2-,3+,4+/m1/s1
5027-63-4Relevant articles and documents
Crystal structure of uronate dehydrogenase from Agrobacterium tumefaciens
Parkkinen, Tarja,Boer, Harry,Jaenis, Janne,Andberg, Martina,Penttilae, Merja,Koivula, Anu,Rouvinen, Juha
experimental part, p. 27294 - 27300 (2012/03/27)
Uronate dehydrogenase from Agrobacterium tumefaciens (AtUdh) belongs to the short-chain dehydrogenase/reductase superfamily and catalyzes the oxidation of D-galacturonic acid and D-glucuronic acid with NAD+ as a cofactor. We have determined the crystal structures of an apo-form of AtUdh, a ternary form in complex with NADH and product (substrate-soaked structure), and an inactive Y136A mutant in complex with NAD+. The crystal structures suggest AtUdh to be a homohexamer, which has also been observed to be the major form in solution. The monomer contains a Rossmann fold, essential for nucleotide binding and a common feature of the short-chain dehydrogenase/reductase family enzymes. The ternary complex structure reveals a product, D-galactaro-1,5-lactone, which is bound above the nicotinamide ring. This product rearranges in solution to D-galactaro-1,4-lactone as verified by mass spectrometry analysis, which agrees with our previous NMR study. The crystal structure of the mutant with the catalytic residue Tyr-136 substituted with alanine shows changes in the position of Ile-74 and Ser-75. This probably altered the binding of the nicotinamide end of NAD+, which was not visible in the electron density map. The structures presented provide novel insights into cofactor and substrate binding and the reaction mechanism of AtUdh. This information can be applied to the design of efficient microbial conversion of D-galacturonic acid-based waste materials.
