5028-20-6

Basic information

• Product Name: N2-METHYL-PYRIDINE-2,3-DIAMINE
• Synonyms: IFLAB-BB F2113-0168;N~2~-Methyl-2,3-pyridinediaMine (SALTDATA: FREE);N2-METHYL-PYRIDINE-2,3-DIAMINE;2-N-METHYLPYRIDINE-2,3-DIAMINE
• CAS NO: 5028-20-6
• Molecular Formula: C₆H₉N₃
• Molecular Weight: 123.15576
• Mol File: 5028-20-6.mol
• Article Data: 23

Chemical Properties

• Melting Point: 100-101 °C
• Boiling Point: 303.553 °C at 760 mmHg
• Flash Point: 137.384 °C
• Appearance: /
• Density: 1.18 g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.652
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 7.04±0.10(Predicted)
• CAS DataBase Reference: N2-METHYL-PYRIDINE-2,3-DIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N2-METHYL-PYRIDINE-2,3-DIAMINE(5028-20-6)
• EPA Substance Registry System: N2-METHYL-PYRIDINE-2,3-DIAMINE(5028-20-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 5028-20-6(Hazardous Substances Data)

Usage

Description

N2-METHYL-PYRIDINE-2,3-DIAMINE, also known as 2,3-diamino-N-methylpyridine, is an organic compound with the molecular formula C6H8N4. It is a heterocyclic compound featuring a pyridine ring with two amine groups at the 2nd and 3rd positions and a methyl group attached to the nitrogen at the 2nd position. N2-METHYL-PYRIDINE-2,3-DIAMINE is known for its reactivity and is commonly used as a building block in the synthesis of various pharmaceuticals and chemical compounds.

Uses

Used in Pharmaceutical Synthesis:
N2-METHYL-PYRIDINE-2,3-DIAMINE is used as a synthetic reagent for the production of imidazopyridines, which exhibit tuberculostatic activity. These imidazopyridines are compounds that have shown potential in the treatment of tuberculosis by inhibiting the growth of Mycobacterium tuberculosis, the bacterium responsible for the disease.
In the pharmaceutical industry, N2-METHYL-PYRIDINE-2,3-DIAMINE serves as a key intermediate in the synthesis of various drug candidates, particularly those with potential applications in treating tuberculosis and other related infections. Its unique chemical structure allows for the development of novel compounds with improved efficacy and reduced side effects, making it a valuable asset in the ongoing fight against drug-resistant tuberculosis.

InChI:InChI=1/C6H9N3/c1-8-6-5(7)3-2-4-9-6/h2-4H,7H2,1H3,(H,8,9)

Upstream product

• 6298-19-7 2-chloro-3-aminopyridine 
• 74-89-5 methylamine 
• 4093-88-3 2-(methylamino)-3-nitropyridine 
• 7440-05-3 palladium 
• 1281006-64-1 N-benzyl-N-methyl-3-nitropyridin-2-amine 
• 5470-18-8 2-Chloro-3-nitropyridine 
• 462-08-8 pyridin-3-ylamine 
• 99314-91-7 N²,N³-dibenzyloxycarbonyl-2,3-diaminopyridine 
• 99314-95-1 N³-benzyloxycarbonyl-N²-methoxycarbonyl-2,3-diaminopyridine 
• 99314-92-8 N²-amino-N³-benzyloxycarbonylaminopyridine 
• 452-58-4 2,3-Diaminopyridine 
• 1480-87-1 2-fluoro-3-nitropyridine 
• 99315-00-1 (3-Amino-pyridin-2-yl)-carbamic acid methyl ester 

Downstream Products

• 123494-89-3 3-(3-Methyl-3H-2-imidazo<4,5-b>pyridine)propionic acid 
• 21991-39-9 3-methyl-1,3-dihydro-imidazo[4,5-b]pyridin-2-one 
• 133465-80-2 (E)-2-(3-Methyl-3H-imidazo[4,5-b]pyridin-2-yl)-3-phenyl-acrylonitrile 
• 133465-84-6 (Z)-2-(3-Methyl-3H-imidazo[4,5-b]pyridin-2-yl)-3-phenyl-thioacrylamide 
• 133465-82-4 (E)-3-(4-Hydroxy-3-methoxy-phenyl)-2-(3-methyl-3H-imidazo[4,5-b]pyridin-2-yl)-acrylonitrile 
• 133465-83-5 (E)-3-(4-Diethylamino-phenyl)-2-(3-methyl-3H-imidazo[4,5-b]pyridin-2-yl)-acrylonitrile 
• 133465-86-8 (Z)-3-(4-Hydroxy-3-methoxy-phenyl)-2-(3-methyl-3H-imidazo[4,5-b]pyridin-2-yl)-thioacrylamide 
• 133465-81-3 (E)-3-(3,4-Dimethoxy-phenyl)-2-(3-methyl-3H-imidazo[4,5-b]pyridin-2-yl)-acrylonitrile 
• 133465-87-9 (Z)-3-(4-Diethylamino-phenyl)-2-(3-methyl-3H-imidazo[4,5-b]pyridin-2-yl)-thioacrylamide 
• 133465-85-7 (Z)-3-(3,4-Dimethoxy-phenyl)-2-(3-methyl-3H-imidazo[4,5-b]pyridin-2-yl)-thioacrylamide 
• 133465-78-8 (3-Methyl-3H-imidazo[4,5-b]pyridin-2-yl)-acetic acid [1-(4-hydroxy-3-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide 
• 133465-77-7 (3-Methyl-3H-imidazo[4,5-b]pyridin-2-yl)-acetic acid [1-(3,4-dimethoxy-phenyl)-meth-(E)-ylidene]-hydrazide 
• 41231-05-4 2,3-Dimethylimidazo<4,5-b>pyridine 
• 1097725-72-8 3-methyl-2-N-(p-toluenesulfonyl)aminoimidazo[4,5-b]pyridine 

Relevant articles and documents

Novel imidazo[4,5-b]pyridine derived acrylonitriles: A combined experimental and computational study of their antioxidative potential

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The invention relates to 5,10-dihydropyrido[2',3':5,6]pyrazolo[2,3-e][1,2,4]triazine compounds shown in general formula I, and their optical activators or racemates or their pharmaceutically acceptable salts, hydrates or solvates, wherein substituents R1,