50298-88-9 Usage
Description
17,18-Dehydroapovinvamine is a naturally occurring alkaloid compound that is found as an impurity in Vincamine (V314030), a nootropic agent used to combat the effects of aging and improve cognitive function. It is derived from the plant Vinca minor and has been the subject of research due to its potential therapeutic properties.
Uses
Used in Pharmaceutical Industry:
17,18-Dehydroapovinvamine is used as an impurity in the production of Vincamine, a nootropic agent, for its cognitive-enhancing properties. It is particularly utilized in the development of drugs aimed at combating the effects of aging and improving brain function.
Used in Nootropic Applications:
17,18-Dehydroapovinvamine is used in conjunction with other nootropics, such as piracetam, to enhance cognitive function and memory. Its presence in Vincamine contributes to the overall effectiveness of these nootropic combinations.
Used in Peripheral Vasodilation:
As a component of Vincamine, 17,18-Dehydroapovinvamine contributes to the drug's peripheral vasodilatory effects, increasing blood flow to the brain and potentially improving cognitive performance and overall brain health.
Check Digit Verification of cas no
The CAS Registry Mumber 50298-88-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,2,9 and 8 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 50298-88:
(7*5)+(6*0)+(5*2)+(4*9)+(3*8)+(2*8)+(1*8)=129
129 % 10 = 9
So 50298-88-9 is a valid CAS Registry Number.
50298-88-9Relevant articles and documents
Synthesis of new eburnamine-type alkaloid via direct hydroalkoxylation
Liu, Xiong,Yang, Dong-Liang,Liu, Jia-Jia,Zhou, Jing,Zhao, Nana
, p. 816 - 822 (2014)
This study concerns the preparation of a new eburnamine-type alkaloid, methyl (3α,14β,15β,16α)-17,18-didehydro-14,15- dihydroeburnamine-15-methoxy-14-carboxylate (VIII). This alkaloid was prepared from (+)-17,18-dehydroapovincamine (V) using Lewis acid and/or ion exchange resin as catalyst. The hydroalkoxylation reaction of V with methanol was investigated in terms of catalyst, solvent, temperature, and time of reaction. A one-pot method for synthetising this alkaloid was established. The optimal conditions for the reaction are discussed.
