5032-92-8

Basic information

• Product Name: pentafluorophenyl phosphinic acid
• Synonyms: pentafluorophenyl phosphinic acid
• CAS NO: 5032-92-8
• Molecular Weight: 232.046
• Mol File: 5032-92-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: pentafluorophenyl phosphinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: pentafluorophenyl phosphinic acid(5032-92-8)
• EPA Substance Registry System: pentafluorophenyl phosphinic acid(5032-92-8)

Safety Data

• Hazardous Substances Data: 5032-92-8(Hazardous Substances Data)

Upstream product

• 7196-52-3 Pentafluorphenylphosphonigsaeure 
• 344-04-7 bromopentafluorobenzene 
• 13648-83-4 bis(diethylamino)-2,3,4,5,6-pentafluorophenylphosphane 
• 5032-91-7 pentafluorophenyl dichlorophosphine 
• 879-05-0 2,3,4,5,6-pentafluorophenylmagnesium bromide 
• 144776-54-5 2-Pentafluorophenyl-[1,3,2]dioxaphospholane 

Downstream Products

• 56875-35-5 pentafluorophenylphosphonic acid 

Relevant articles and documents

Bis(diethylamino)pentafluorophenylphosphane as Valuable Precursor for the Design of Tetrafluorophenylphosphanes, Tetrafluorophenylphosphinic and -phosphonic Acids

Facile replacement of the p-fluorine atom in bis(diethylamino)pentafluorophenylphosphane [(Et2N)2PC6F5] by organolithium derivatives LiR (R = CH3, n-Bu, Ph), lithium alkoxides (R = OMe, OEt) and amides (NMe2, NEt2) is described. The obtained phosphanes p-R-C6F4-P(NEt2)2 are fully characterized. Their acid-catalyzed hydrolysis affords the corresponding phosphinic acids p-R-C6F4-P(O)(H)OH, which are smoothly oxidized by treatment with a mixture of DMSO/I2 to phosphonic acids p-R-C6F4-P(O)(OH)2.

Synthesis and characterization of some perfluorophenylphosphine derivatives

Bis(pentafluorophenyl)chlorophosphine and pentafluorophenyldichlorophosphine are prepared in good yields from pentafluorophenylmagnesium bromide and phosphorus trichloride. The reactions of the halophosphines with the Lewis bases water, ammonia, dimethylamine, and 2-methylaziridine produced substituted phosphines. Oxidative chlorination of bis(pentafluorophenyl)phosphinamide followed by dehydrohalogenation gave perfluorophenylphosphonitriles. The infrared and pertinent proton magnetic resonance spectra of these compounds are discussed.