50395-07-8

Basic information

• Product Name: 16-E-(benzylidene)-3-methoxy-1,3,5?(10)-estratriene-17-one
• Synonyms: 16-E-(benzylidene)-3-methoxy-1,3,5?(10)-estratriene-17-one
• CAS NO: 50395-07-8
• Molecular Weight: 372.507
• Mol File: 50395-07-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 16-E-(benzylidene)-3-methoxy-1,3,5?(10)-estratriene-17-one(CAS DataBase Reference)
• NIST Chemistry Reference: 16-E-(benzylidene)-3-methoxy-1,3,5?(10)-estratriene-17-one(50395-07-8)
• EPA Substance Registry System: 16-E-(benzylidene)-3-methoxy-1,3,5?(10)-estratriene-17-one(50395-07-8)

Safety Data

• Hazardous Substances Data: 50395-07-8(Hazardous Substances Data)

Upstream product

• 1624-62-0 estrone 3-methyl ether 
• 100-52-7 benzaldehyde 
• 59877-96-2 16-(hydroxymethylene)-3-methoxyestra-1,3,5⁽¹⁰⁾-trien-17-one 
• 108-86-1 bromobenzene 
• 18011-90-0 (8R,9S,13S,14S)-3-methoxy-13-methyl-16-methylene-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-one 

Relevant articles and documents

Synthesis of 16-E-([aryl]idene)-3-methoxy-estrones by a palladium catalysed Mizoroki-Heck reaction

16-E-Arylidene-3-methoxy-estrones were synthesized using a palladium catalysed Mizoroki-Heck reaction. This methodology tolerates various functional groups and gives the corresponding products in yields between 14 and 99%, which were strongly dependent on the electronic character of the aryl halides.