50427-08-2

Basic information

• Product Name: 6-methyl-2-(phenylamino)pyrimidin-4(1H)-one
• Synonyms: 2-Anilino-6-methylpyrimidin-4(3H)-one; 2-Anilino-6-methylpyrimidin-4-ol; 4(3H)-pyrimidinone, 6-methyl-2-(phenylamino)-; 4-pyrimidinol, 6-methyl-2-(phenylamino)-
• CAS NO: 50427-08-2
• Molecular Formula: C₁₁H₁₁N₃O
• Molecular Weight: 201.2245
• Mol File: 50427-08-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 331.4°C at 760 mmHg
• Flash Point: 154.2°C
• Density: 1.23g/cm³
• Vapor Pressure: 0.000156mmHg at 25°C
• Refractive Index: 1.628
• CAS DataBase Reference: 6-methyl-2-(phenylamino)pyrimidin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-2-(phenylamino)pyrimidin-4(1H)-one(50427-08-2)
• EPA Substance Registry System: 6-methyl-2-(phenylamino)pyrimidin-4(1H)-one(50427-08-2)

Safety Data

• Hazardous Substances Data: 50427-08-2(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 141-97-9 ethyl acetoacetate 
• 6685-76-3 phenylguanidinium hydrogencarbonate 
• 2002-16-6 1-phenylguanidine 
• 55996-28-6 6-methyl-2-methoxy-4(3H)-pyrimidinone 
• 6328-58-1 6-methyl-2-methylsulfanyl-3H-pyrimidin-4-one 
• 53736-37-1 2-nitroamino-4(3H)-pyrimidinone 

Downstream Products

• 6967-54-0 6-methyl-2-phenylamino-4-chloropyrimidine 
• 110235-47-7 mepanipyrim 
• 1412896-90-2 4-(4-iodophenyl)amino-6-methyl-2-phenylaminopyrimidine hydrochloride 
• 53112-26-8 4-methyl-N-phenylpyrimidin-2-amine 

Relevant articles and documents

Anilinopyrimidine compound and medical use thereof

The invention relates to an anilinopyrimidine represented by general formula (I), and a pharmaceutically acceptable salt, a solvate and a prodrug thereof. Substituent groups R1, R2, R3, R4, R5, R6, R7, R8, R9, Q and n in the general formula (I) are as def

Effect of the structural modification of 2-benzylamino-4-(4-iodophenyl) amino-6-methylpyrimidine on the biological activity of its derivatives

Abstract-Modification of the aliphatic-aromatic moiety in the 2-benzylmino-4-(4-iodophenyl)amino-6- methylpyrimidine leads to a change in the site of biological action of the formed structural analogs. Pleiades Publishing, Ltd., 2012.

6-ALKYL- AND 5,6-DIALKYL-2-METHOXY-4-(3H)-PYRIMIDINONES IN THE TRANSFORMATIONS OF PYRIMIDINES. CONVERSION INTO 2-SUBSTITUTED AMINO- AND 4-CHLORO-PYRIMIDINE-DERIVATIVES

6-Alkyl- and 5,6-dialkyl-2-methoxy-4(3H)-pyrimidinones are transformed into the 2-alkyl (and 2-aryl)amino-derivatives, in good yield, by reaction with the corresponding amines.Treatment with SOCl2-DMF gives 6-alkyl- and 5,6-dialkyl-2-methoxy-4-chloropyrimidines.