50437-74-6Relevant articles and documents
A Domino Route toward Polysubstituted Pyrroles from 2-Imidazolines and Electron-Deficient Alkynes
Festa, Alexey A.,Golantsov, Nikita E.,Golubenkova, Alexandra S.,Varlamov, Alexey V.,Voskressensky, Leonid G.
, (2020)
The reaction of 1,2-disubstituted 2-imidazolines with electron-deficient alkynes proceeds as a pseudo-three-component process and forms imidazolidines with an N-vinylpropargylamine fragment. Heating the resulting imidazolidines in xylene on air leads to a
One-pot triflic anhydride-mediated synthesis of 1,2-disubstituted 2-imidazolines from N-(2-haloethyl)amides and amines
Ellsworth, Alyssa A.,Magyar, Christina L.,Hubbell, Grace E.,Theisen, Chelsea C.,Holmes, Daniel,Mosey, R. Adam
, p. 6380 - 6389 (2016/09/23)
A one-pot synthesis of 1,2-disubstituted 2-imidazolines from N-(2-haloethyl)amides has been developed. The reaction affords high yields of diverse 1,2-disubstituted 2-imidazolines from triflic anhydride-mediated dehydration of amides followed by installat