50460-66-7

Basic information

• Product Name: 2-Amino-6-chloro-N-o-tolylbenzamide
• Synonyms: 2-Amino-6-chloro-N-o-tolylbenzamide
• CAS NO: 50460-66-7
• Molecular Weight: 260.723
• Mol File: 50460-66-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Amino-6-chloro-N-o-tolylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-6-chloro-N-o-tolylbenzamide(50460-66-7)
• EPA Substance Registry System: 2-Amino-6-chloro-N-o-tolylbenzamide(50460-66-7)

Safety Data

• Hazardous Substances Data: 50460-66-7(Hazardous Substances Data)

Upstream product

• 95-53-4 o-toluidine 
• 5344-49-0 2-chloro-6-nitrobenzoic acid 
• 2148-56-3 2-chloro-6-aminobenzoic acid 

Downstream Products

• 69123-66-6 5-Chloro-2-chloromethyl-3-o-tolyl-3H-quinazolin-4-one 

Relevant articles and documents

Substituted aminopyrimidine compounds and their method and use thereof

The invention relates to a new aminopyrimidine compound and an application thereof as a drug for treating disorder or diseases related to PI3-kinase abnormity in a free form or a pharmaceutically acceptable salt and preparation form. The invention also relates to a pharmaceutical composition which contains the new aminopyrimidine compound and an application of the pharmaceutical composition in treating mammal disorder or diseases and especially treating human disorder or diseases related to the PI3-kinase abnormity, such as treatment of immunity and inflammatory diseases of PI3-kinase regulation which plays a leading role in a leucocyte function and treatment of proliferative diseases which are related to PI3-kinase activity and include but not limited to leukaemia and solid tumor.

Inhibitors of human phosphatidylinositol 3-kinase delta

Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (PI3Kδ) activity, and methods of treating diseases, such as disorders of immunity and inflammation, in which PI3Kδ plays a role in leukocyte function are disclosed. Preferably, the methods