50463-29-1

Basic information

• Product Name: 1,2-bis(1,3-benzodioxol-5-yl)ethanone
• CAS NO: 50463-29-1
• Molecular Formula: C₁₆H₁₂O₅
• Molecular Weight: 284.2635
• Mol File: 50463-29-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 473.9°C at 760 mmHg
• Flash Point: 213.5°C
• Density: 1.393g/cm³
• Vapor Pressure: 3.8E-09mmHg at 25°C
• Refractive Index: 1.635
• CAS DataBase Reference: 1,2-bis(1,3-benzodioxol-5-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-bis(1,3-benzodioxol-5-yl)ethanone(50463-29-1)
• EPA Substance Registry System: 1,2-bis(1,3-benzodioxol-5-yl)ethanone(50463-29-1)

Safety Data

• Hazardous Substances Data: 50463-29-1(Hazardous Substances Data)

Usage

Synonyms

MDBD

Physical appearance

Yellowish-brown crystalline powder

Usage

Intermediate in the synthesis of pharmaceuticals and agrochemicals

Role

Versatile building block in organic chemistry

Applications

a. Development of new drugs
b. Production of insecticides and herbicides
c. Manufacturing of fragrances, flavors, and dyes

Purity

High purity

Stability

Stable compound

Industry

Valuable in the chemical industry

Upstream product

• 76306-40-6 (E)-1,2-di-(3',4'-methylenedioxyphenyl)-ethylene 
• 120-57-0 piperonal 
• 90522-24-0 (2R*,3R*)-2,3-bis(benzo[d][1,3]dioxol-5-yl)oxirane 
• 134542-45-3 <(Dimethylamino)(1,3-benzodioxol-5-yl)methyl>phosphonic Bis(dimethylamide) 
• 4720-82-5 piperoin 

Downstream Products

• 93098-04-5 ethyl 4-hydroxy-3,4-di-(4-methoxyphenyl)-2-butenoate 
• 93098-09-0 ethyl 3-(3,4-methylenedioxybenzoyl)-3-(3,4-methylenedioxyphenyl)propionate 
• 1226-42-2 1,2-bis(4-methoxyphenyl)-1,2-ethanedione 

Relevant articles and documents

The reaction of arylaldehydes with hexamethylphosphorous triamide and the use of the resulting products for the synthesis of enamines and deoxybenzoins

The reaction between the arylaldehydes 1a,b and hexamethylphosphorous triamide 2 leads to the [aryl(dimethylamino)methyl]phosphonic bis(dimethylamides) 3a,b. These can be easily deprotonated by butyllithium in 1,2-dimethoxyethane and condensed with arylaldehydes to afford enamines 4a-f or deoxybenzoins 5a-f in fair to good yield.

IODOTRIMETHYLSILANE REDUCTION OF BENZOINS: SYNTHESIS OF DEOXYBENZOINS AND TETRAARYLFURANS

Benzoins react readily with idotriethylsilane to produce, in many cases, mixtures of deoxybenzoins and tetraarylfurans.