50463-82-6

Basic information

• Product Name: (2R)-(+)-phenylmethyl 2-formylpyrrolidine-1-carboxylate
• CAS NO: 50463-82-6
• Molecular Weight: 233.267
• Mol File: 50463-82-6.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: (2R)-(+)-phenylmethyl 2-formylpyrrolidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-(+)-phenylmethyl 2-formylpyrrolidine-1-carboxylate(50463-82-6)
• EPA Substance Registry System: (2R)-(+)-phenylmethyl 2-formylpyrrolidine-1-carboxylate(50463-82-6)

Safety Data

• Hazardous Substances Data: 50463-82-6(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 200499-57-6 (2R,4'S)-N-Benzyloxycarbonyl-2-(2',2'-dimethyl-1',3'-dioxolan-4'-yl)pyrrolidine 
• 200499-52-1 (R)-4-Azido-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-butyric acid methyl ester 
• 200499-54-3 (R)-4-Azido-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-butyraldehyde 
• 200499-55-4 (R)-2-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]pyrrolidine 
• 136963-32-1 methyl 2,3-dideoxy-5,6-O-isopropylidene-4-O-p-tolylsulfonyl-D-erythro-hexonate 
• 68832-13-3 D-prolinol 
• 200499-58-7 (R)-1-benzyloxycarbonyl-2-[(S)-1,2-dihydroxyethyl]pyrrolidine 
• 182210-00-0 methyl (2R)-(benzyloxycarbonyl)pyrrolidine-2-carboxylate 
• 72597-18-3 (2R)-(+)-phenylmethyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate 

Downstream Products

• 146727-84-6 benzyl (2R)-2-((1E)-3-ethoxy-3-oxoprop-1-enyl)pyrrolidine-1-carboxylate 
• 108807-54-1 Z-D-prolinal semicarbazone 
• 1036404-01-9 (R)-(N-benzyloxycarbonyl)-2-(2-oxoethyl)pyrrolidine 
• 1327157-87-8 (R)-benzyl 2-((R)-1-hydroxypent-4-en-1-yl)pyrrolidine-1-carboxylate 
• 1403231-83-3 (R)-benzyl 2-((S)-1-hydroxypent-4-en-1-yl)pyrrolidine-1-carboxylate 
• 953429-99-7 C₁₆H₂₂NO₉P 

Relevant articles and documents

FUMAGILLOL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME

Disclosed herein, in part, are fumagillol compounds and methods of use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making fumagillol compounds are provided. The compounds are contemplated to have activity against methionyl aminopeptidase 2.

INDANOL DERIVATIVE

The present invention provides a compound having the following general formula (I) which is useful as a neurokinin receptor antagonist: (wherein, R1, R2: optionally substituted (hetero)aryl, R3: -CO-R4, -CO-O-R4, etc., R4: alkyl, cycloalkyl, etc., A: CH2, CO, SO2, B: a single bond, etc., D: oxygen, CH2, E: alkylene, alkenylene, n: 1 to 3).

Synthesis and α4β2 nicotinic affinity of unichiral 5-(2-pyrrolidinyl)oxazolidinones and 2-(2-pyrrolidinyl)benzodioxanes

The RS and SR enantiomers of 2-oxazolidinone and 1,4-benzodioxane bearing a 2-pyrrolidinyl substituent at the 5- and 2-position, respectively, were synthesized as candidate nicotinoids. One of the two benzodioxane stereoisomers reasonably fits the pharmac