50571-26-1

Basic information

• Product Name: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-(hydrogen phosphonate)
• CAS NO: 50571-26-1
• Molecular Formula: C31H33N2O9P
• Molecular Weight: 608.585
• Mol File: 50571-26-1.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-(hydrogen phosphonate)(CAS DataBase Reference)
• NIST Chemistry Reference: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-(hydrogen phosphonate)(50571-26-1)
• EPA Substance Registry System: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-(hydrogen phosphonate)(50571-26-1)

Safety Data

• Hazardous Substances Data: 50571-26-1(Hazardous Substances Data)

Upstream product

• 1000692-08-9 C₃₃H₃₇N₂SPO₈ 
• 50-89-5 thymidine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 104655-76-7 5'-O-dimethoxytrityl thymidine 3'-O-phosphorbisdiethylamidite 
• 98796-51-1 5'-O-(4,4'-dimethoxytrityl)-2'-deoxythymidine-3'-O-[O-(2-cyanoethyl)-N,N'-diisopropylphosphoramidite] 
• 104655-82-5 5'-O-(p,p'-dimethoxytrityl)thymidine 3'-(allyl N,N-diisopropylphosphoramidite) 
• 89849-93-4 5'-O-dimethoxytritylthymidin-3'-yl 3'-O-(1,3-benzodithiol-2-yl)thymidin-5'-yl H-phosphonate 
• 157793-52-7 p-chlorophenyl 5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl phosphonate 
• 160056-33-7 Phenyl 5'-O-dimethoxytritylthymidin-3'-yl phosphonate 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 120942-89-4 Phosphorous acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester bis-(2,2,2-trifluoro-1-trifluoromethyl-ethyl) ester 
• 102987-83-7 5′-O-(4,4′-dimethoxytrityl)thymidine-3′-O-[2-cyanoethyl]phosphonate 
• 104684-77-7 C₃₄H₃₇N₂O₉P 

Downstream Products

• 1000692-09-0 C₃₅H₄₁N₂SPO₈ 
• 1000692-10-3 C₄₇H₅₉N₄SPO₁₂Si 
• 1000692-11-4 C₅₈H₇₇N₂SPO₈ 
• 1000692-08-9 C₃₃H₃₇N₂SPO₈ 
• 135704-44-8 C₃₆H₄₁N₂O₁₀P 
• 105784-94-9 5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl ethyl phosphonate 
• 1392279-62-7 C₄₆H₅₁N₂O₁₃P 
• 1392279-58-1 C₄₅H₄₉N₂O₁₃P 
• 1396637-30-1 C₆H₁₅N*C₄₅H₄₉N₂O₁₃P 
• 1392279-50-3 C₂₂H₂₉N₂O₁₀P 
• 1396637-20-9 C₆H₁₅N*C₄₆H₅₁N₂O₁₃P 
• 1392279-53-6 C₂₃H₃₁N₂O₁₀P 
• 157793-52-7 p-chlorophenyl 5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl phosphonate 
• 102987-86-0 C₄₈H₄₉N₄O₁₄P 

Relevant articles and documents

First synthesis of carbocyclic oligothymidylates

5'-O-(dimethoxytrityl)-(+)-carbocyclic thymidine 1 is converted into different 3'-substituted intermediates 2a-c following standard procedures. From these compounds stereochemically pure carbocyclic oligothymidylates 4 are obtained using solid phase synthetic methods.

Nucleoside H-phosphonates, XXII: Synthesis and properties of new nucleotide analogues - H-phosphonothiolate diesters

Condensation of nucleoside 3′-H-phosphonate monoesters with various thiols, promoted by condensing agents, provides a convenient access to a new class of H-phosphonate analogues, H-phosphonothiolate diesters. Chemical properties, relevant to possible appl

Use of ammonium aryl H-phosphonates in the preparation of nucleoside H-phosphonate building blocks

Ammonium 4-methylphenyl H-phosphonate 4c was used in the conversion of 5'-0-(dimethoxy-trityl)-2'-deoxynucleoside derivatives 6 into the corresponding 3'-H-phosphonates 2, which were isolated in a high state of purity and in high yield.