50590-07-3

Basic information

• Product Name: 4-IODO-3-NITROPHENOL
• Synonyms: 3-Iodo-4-nitrophenol.;4-IODO-3-NITROPHENOL 97%;Phenol, 3-iodo-4-nitro-
• CAS NO: 50590-07-3
• Molecular Formula: C₆H₄INO₃
• Molecular Weight: 265.01
• Product Categories: Aromatic Phenols
• Mol File: 50590-07-3.mol
• Article Data: 4

Chemical Properties

• Melting Point: 153-159 °C
• Boiling Point: 382.525 °C at 760 mmHg
• Flash Point: 185.145 °C
• Appearance: /
• Density: 2.176
• Vapor Pressure: 3.05E-05mmHg at 25°C
• Refractive Index: 1.71
• Storage Temp.: 2-8°C(protect from light)
• PKA: 6.39±0.10(Predicted)
• CAS DataBase Reference: 4-IODO-3-NITROPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-IODO-3-NITROPHENOL(50590-07-3)
• EPA Substance Registry System: 4-IODO-3-NITROPHENOL(50590-07-3)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 36/37/39-26
• Hazardous Substances Data: 50590-07-3(Hazardous Substances Data)

Usage

General Description

4-Iodine-3-nitrophenol is a chemical compound with the molecular formula C6H4INO3. This synthetic compound, often presented as a clear light yellow crystalline solid in its pure form, is associated with applications in various fields such as chemical synthesis and pharmacology. It is characterized by the presence of iodine and nitrate chemical groups, which gives it unique properties such as high reactivity. Its nitrophenol ring structure allows for efficient electron delocalization, which is essential in many chemical reactions. Handling 4-iodine-3-nitrophenol requires caution, as it is considered hazardous and can be an irritant to skin and eyes.

InChI:InChI=1/C6H4INO3/c7-5-2-1-4(9)3-6(5)8(10)11/h1-3,9H

Upstream product

• 7664-93-9 sulfuric acid 
• 626-02-8 3-Iodophenol 
• 799767-58-1 3-iodo-4-nitroso-phenol 
• 39495-50-6 iodo-[1,4]benzoquinone-1-oxime 

Downstream Products

• 139277-45-5 6-hydroxy-2-iodo-3-nitrobenzaldehyde 
• 214279-40-0 3-iodo-4-nitroanisol 
• 197095-75-3 6-Methoxymethoxy-3-nitro-2-{3-[2-(tetrahydro-pyran-2-yloxy)-ethoxy]-prop-1-ynyl}-benzaldehyde 
• 197095-76-4 6-(6-hydroxy-4-oxa-hex-1-ynyl)-5-nitrosalicylaldehyde 
• 139277-46-6 2-Iodo-6-methoxymethoxy-3-nitro-benzaldehyde 
• 53398-97-3 5-iodo-2,4-dinitro-phenol 
• 66416-73-7 p-hydroxy-o-iodoaniline 
• 4840-88-4 3-iodo-2,4,6-trinitro-phenol 
• 80653-82-3 4-nitro-3-(4-pyridinyl)phenol 
• 1092108-49-0 4-(allyloxy)-2-iodo-1-nitrobenzene 
• 35350-40-4 bis-(5-methoxy-2-nitro-phenyl)-disulfide 
• 616-74-0 4,6-dinitroresorcinol 

Relevant articles and documents

HETEROARYL COMPOUNDS AS PDE10A INHIBITORS

The present invention provides heteroaryl compounds as Phosphodiesterase 10A (PDE I OA) inhibitors. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders by inhibiting Phosphodiesterase 10A enzyme. Also provided herein are processes for preparing compounds described herein, Formula (I), intermediates used in their synthesis, pharmaceutical compositions thereof.

Geldanamycin derivative inhibition of HGF/SF-mediated Met tyrosine kinase receptor-dependent urokinase-plasminogen activation

Ansamycins, including geldanamycin and the derivative 17-allylamino-17- demethoxygeldanamycin, and radicicol are known for their ability to tightly bind to the ATP-binding site of the amino-terminal domain region of heat shock protein 90. We have found that geldanamycin and some of its derivatives can inhibit hepatocyte growth factor/scatter factor-mediated Met tyrosine kinase receptor-dependent urokinase-plasminogen activation at femtomolar levels. Assessment is made of structural requirements for such an activity and evidence is given that distinguishes the target of such an activity from that of heat shock protein 90.