50608-12-3

Basic information

• Product Name: 5-tert-butyl-N-methyl-1,3,4-thiadiazol-2-amine
• Synonyms: 5-tert-butyl-N-methyl-1,3,4-thiadiazol-2-amine;5-(1,1-Dimethylethyl)-N-methyl-1,3,4-thiadiazol-2-amine;5-tert-butyl-2-MethylaMino-1,3,4-thiadiazole
• CAS NO: 50608-12-3
• Molecular Formula: C₇H₁₃N₃S
• Molecular Weight: 171.26322
• EINECS: 256-651-8
• Mol File: 50608-12-3.mol
• Article Data: 6

Chemical Properties

• Melting Point: 80-82 °C
• Boiling Point: 253.9°C at 760 mmHg
• Flash Point: 107.4°C
• Appearance: /
• Density: 1.13g/cm³
• Vapor Pressure: 0.0178mmHg at 25°C
• Refractive Index: 1.557
• PKA: 4.21±0.10(Predicted)
• CAS DataBase Reference: 5-tert-butyl-N-methyl-1,3,4-thiadiazol-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-tert-butyl-N-methyl-1,3,4-thiadiazol-2-amine(50608-12-3)
• EPA Substance Registry System: 5-tert-butyl-N-methyl-1,3,4-thiadiazol-2-amine(50608-12-3)

Safety Data

• Hazardous Substances Data: 50608-12-3(Hazardous Substances Data)

Usage

Description

5-tert-butyl-N-methyl-1,3,4-thiadiazol-2-amine is an organic compound with the molecular formula C6H12N4S. It is a heterocyclic compound featuring a thiadiazole ring, which is a five-membered ring containing sulfur and nitrogen atoms. 5-tert-butyl-N-methyl-1,3,4-thiadiazol-2-amine is known for its chemical reactivity and is often utilized as a synthetic intermediate in the production of various chemicals and pharmaceuticals.

Uses

Used in Chemical Synthesis:
5-tert-butyl-N-methyl-1,3,4-thiadiazol-2-amine is used as a synthetic intermediate for the production of various chemicals, including pharmaceuticals and agrochemicals. Its unique chemical structure allows it to be a versatile building block in the synthesis of complex molecules.
Used in Herbicide Production:
In the agricultural industry, 5-tert-butyl-N-methyl-1,3,4-thiadiazol-2-amine is used in the synthesis of Tebuthiuron (T013620), a nonselective broad-spectrum herbicide. This herbicide is effective in controlling a wide range of weeds, including woody and herbaceous plants, making it a valuable tool for farmers and gardeners to maintain healthy crops and landscapes.
5-tert-butyl-N-methyl-1,3,4-thiadiazol-2-amine 5-tert-butyl-N-methyl-1,3,4-thiadiazol-2-amine plays a crucial role in the development of various applications across different industries, particularly in chemical synthesis and agriculture. Its unique properties and reactivity make it a valuable component in the creation of new and innovative products.

InChI:InChI=1/C7H13N3S/c1-7(2,3)5-9-10-6(8-4)11-5/h1-4H3,(H,8,10)

Upstream product

• 42826-42-6 pivalohydrazide 
• 75-98-9 Trimethylacetic acid 
• 3282-30-2 pivaloyl chloride 
• 6610-29-3 4-methylthiosemicarbazide 
• 51672-22-1 4-methyl-1-trimethylacetyl-3-thiosemicarbazide 

Downstream Products

• 34014-18-1 tebuthiuron 
• 106141-32-6 N-(5-tert-butyl-1,3,4-thiadiazol-2-yl)-N-methylcarbamoyl chloride 

Relevant articles and documents

Method for synthesizing 2-methylamino-5-tert-butyl-1,3,4-thiadiazole

The invention provides a method for synthesizing 2-methylamino-5-tert-butyl-1,3,4-thiadiazole. The method comprises the steps that pivalic acid and hydrazine hydrate are taken as raw materials and subjected to a dehydration reaction to obtain an intermediate I; the intermediate I and a vulcanizing agent are subjected to a vulcanization reaction to obtain an intermediate II; the intermediate II issubjected to dehydration and ring closing to obtain an intermediate III; the intermediate III and paraformaldehyde are subjected to a condensation reaction to obtain an intermediate IV; and the intermediate IV is subjected to a reduction reaction to obtain the 2-methylamino-5-tert-butyl-1,3,4-thiadiazole. The problems in the prior art that reaction raw materials are not easy to obtain, the industrial operation is difficult, the reaction process is prone to causing environmental pollution and the like are solved, and the synthetic method which is easy in raw material obtaining, environmentallyfriendly in process and easy to industrialize is provided.

Three nitrogen heterocycle containing 1, 2, 3 - thiadiazole - 5 - a amidine compounds and synthesis

The invention discloses an N-trisubstituted-1,2,3-thiadiazole-5-formamidine compound with three aromatic rings of general formula TDCA and a synthesis method of N-trisubstituted-1,2,3-thiadiazole-5-formamidine compound. The target compound of general formula TDCA is obtained by reacting a compound of general formula B and a compound of general formula A, wherein references of X and Y in the general formula A are the same as those in the general formula TDCA.

Process for preparing the compound 5-t-butyl-2-methylamino-1,3,4-triadiazole

A process for preparing the compound 5-t-butyl-2-methylamino-1,3,4-thiadiazole, STR1 in high yield by the reaction of 4-methyl-3-thiosemicarbazide with pivalic acid in a solution containing both polyphosphoric acid and concentrated sulfuric acid, followed by neutralizing the reaction mixture with a neutralizing mixture comprising an organic solvent and an alkaline substance dissolved in water and separating 5-t-butyl-2-methylamino-1,3,4-thiadiazole from the organic phase.