5061-22-3 Usage
Originator
Naftidan,De Angeli,Italy,1969
Manufacturing Process
15 grams of α-methyl-1-naphthylacetic acid were refluxed with 50 ml of
thionyl chloride during 3 hours. The excess thionyl chloride was removed
under reduced pressure and the product was also isolated by distillation under
reduced pressure. Yield: 15.6 grams (96%). The α-methyl-1-naphthyl acetyl
chloride boils at 120° to 124°C. 1.76 grams of N,N'-di-(β-hydroxyethyl)-
piperazine, 1.9 grams of sodium bicarbonate and 4.45 grams of α-methyl-1-
naphthyl acetyl chloride in 30 ml of anhydrous acetonitrile were refluxed with
stirring during 5 hours. After cooling the mixture was filtered and the acetonitrile evaporated off under reduced pressure. 5.2 grams of crude ester
were obtained. The hydrochloride, melting at 220° to 221°C, may be prepared
by dissolving the ester in absolute ethanol and treating the solution with
anhydrous gaseous hydrogen chloride.
Therapeutic Function
Spasmolytic
Check Digit Verification of cas no
The CAS Registry Mumber 5061-22-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,0,6 and 1 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 5061-22:
(6*5)+(5*0)+(4*6)+(3*1)+(2*2)+(1*2)=63
63 % 10 = 3
So 5061-22-3 is a valid CAS Registry Number.
InChI:InChI=1/C34H38N2O4/c1-25(29-15-7-11-27-9-3-5-13-31(27)29)33(37)39-23-21-35-17-19-36(20-18-35)22-24-40-34(38)26(2)30-16-8-12-28-10-4-6-14-32(28)30/h3-16,25-26H,17-24H2,1-2H3