50622-64-5

Basic information

• Product Name: 1H-Pyrrole-3-propanoic acid, 4-(2-methoxy-2-oxoethyl)-5-methyl-2-[(phenylmethoxy)carbonyl]-, methyl ester
• CAS NO: 50622-64-5
• Molecular Formula: C20H23NO6
• Molecular Weight: 373.406
• Mol File: 50622-64-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-3-propanoic acid, 4-(2-methoxy-2-oxoethyl)-5-methyl-2-[(phenylmethoxy)carbonyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-3-propanoic acid, 4-(2-methoxy-2-oxoethyl)-5-methyl-2-[(phenylmethoxy)carbonyl]-, methyl ester(50622-64-5)
• EPA Substance Registry System: 1H-Pyrrole-3-propanoic acid, 4-(2-methoxy-2-oxoethyl)-5-methyl-2-[(phenylmethoxy)carbonyl]-, methyl ester(50622-64-5)

Safety Data

• Hazardous Substances Data: 50622-64-5(Hazardous Substances Data)

Upstream product

• 123-54-6 acetylacetone 
• 111017-82-4 ethyl 5-methoxycarbonylmethyl-4,6-dioxoheptanoate 
• 39265-95-7 methyl 3-acetyl-4-oxopentanoate 
• 88915-87-1 4-(2-Chloro-acetyl)-3-(2-methoxycarbonyl-ethyl)-5-methyl-1H-pyrrole-2-carboxylic acid benzyl ester 
• 62916-29-4 4-acetyl-3-(2-methoxycarbonyl-ethyl)-5-methyl-pyrrole-2-carboxylic acid benzyl ester 
• 100-51-6 benzyl alcohol 
• 7149-59-9 diethyl 3-oxoadipate 
• 114125-36-9 5-[5-Chloro-4-(2-methoxycarbonyl-ethyl)-3-methoxycarbonylmethyl-2-methyl-2H-pyrrol-2-ylmethyl]-3-(2-methoxycarbonyl-ethyl)-4-methoxycarbonylmethyl-1H-pyrrole-2-carboxylic acid benzyl ester 
• 207971-28-6 3-(2-Methoxycarbonyl-ethyl)-5-[4-(2-methoxycarbonyl-ethyl)-3-methoxycarbonylmethyl-2-methyl-5-phenylselanyl-2H-pyrrol-2-ylmethyl]-4-methoxycarbonylmethyl-1H-pyrrole-2-carboxylic acid benzyl ester 
• 67-56-1 methanol 
• 59562-71-9 benzyl 4-acetyl-3-(2-ethoxycarbonylethyl)-5-methylpyrrole-2-carboxylate 
• 149-73-5 trimethyl orthoformate 
• 111017-83-5 ethyl 3-(2-ethoxycarbonylethyl)-4-methoxycarbonylmethyl-5-methylpyrrole-2-carboxylate 
• 74839-00-2 methyl 5-methyl-4,6-dioxoheptanoate 

Downstream Products

• 50622-67-8 5-acetoxymethyl-3-(2-methoxycarbonyl-ethyl)-4-methoxycarbonylmethyl-pyrrole-2-carboxylic acid benzyl ester 
• 143085-15-8 benzyl 1,2-dimethyl-4-<(methoxycarbonyl)ethyl>-3-<(methoxycarbonyl)methyl>pyrrole-5-carboxylate 
• 72423-57-5 5-benzyloxycarbonyl-4-(2-methoxycarbonylethyl)-3methoxycarbonylmethylpyrrole-2-carboxylic acid 
• 54932-10-4 benzyl 5-formyl-3-(2-methoxycarbonylethyl)-4-methoxycarbonylmethylpyrrole-2-carboxylate 
• 77929-43-2 3-(2-Methoxycarbonyl-ethyl)-4-methoxycarbonylmethyl-5-trichloromethyl-1H-pyrrole-2-carboxylic acid benzyl ester 
• 74855-24-6 5-Chlorocarbonyl-3-(2-methoxycarbonyl-ethyl)-4-methoxycarbonylmethyl-1H-pyrrole-2-carboxylic acid benzyl ester 
• 111807-55-7 2,2,2-trichloroethyl 5-benzyloxycarbonyl-4-(2-methoxycarbonylethyl)-3-methoxycarbonylmethylpyrrole-2-carboxylate 
• 340156-78-7 3-(2-Methoxycarbonyl-ethyl)-4-methoxycarbonylmethyl-5-phenylsulfanylmethyl-1H-pyrrole-2-carboxylic acid benzyl ester 
• 340156-77-6 benzyl 5-(2-mercaptobenzothiazolylmethyl)-3-(2-methoxycarbonylethyl)-4-methoxycarbonylmethylpyrrole-2-carboxylate 
• 206861-06-5 C₃₄H₃₇Cl₃N₂O₁₂ 
• 55305-15-2 3,3'-bis-(2-methoxycarbonyl-ethyl)-4,4'-bis-methoxycarbonylmethyl-1H,1'H-5,5'-methanediyl-bis-pyrrole-2-carboxylic acid dibenzyl ester 
• 231605-74-6 5-benzyloxycarbonylamino-5'-formyl-3',4-di-(2-methoxycarbonylethyl)-3,4'-dimethoxycarbonylmethyl-2,2'-methylenedipyrrole 
• 231605-75-7 5-benzyloxycarbonylamino-5'-hydroxymethyl-3',4-di-(2-methoxycarbonylethyl)-3,4'-dimethoxycarbonylmethyl-2,2'-methylenedipyrrole 
• 231605-76-8 19-benzyloxycarbonylamino-1-formyl-3,8,13,18-tetra-(2-methoxycarbonylethyl)-2,7,12,17-tetra-(methoxycarbonylmethyl)-bilane 

Relevant articles and documents

Biosynthesis of porphyrins and related macrocycles. Part 47. Synthesis and chemistry of 2H-pyrroles (pyrrolenines) related to the proposed spiro-intermediate for porphyrin biosynthesis

It is proposed that the biosynthesis of uroporphyrinogen III 3, the parent precursor of the natural porphyrins, chlorins and corrins, involves a pyrrolenine 2 as a key intermediate, yet methods for the synthesis of such systems are not available. Novel routes for the synthesis of pyrrolenines by desulfurisation of unsaturated thiolactams have now been devised and the chemistry of such compounds has been explored. Enzymic experiments are carried out using a model pyrrolenine indicating that deletion of one of the pyrrole rings of the putative intermediate 2 leads to loss of tight binding.

Ungiftige Alternative fuer einen Schluesselschritt der Porphyrin-Synthese

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Preparation of intermediates for uroporphyrin synthesis.

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