50685-32-0

Basic information

• Product Name: 2-Cyclohexen-1-one, 3-[(3-methoxyphenyl)amino]-5,5-dimethyl-
• CAS NO: 50685-32-0
• Molecular Formula: C15H19NO2
• Molecular Weight: 245.321
• Mol File: 50685-32-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-Cyclohexen-1-one, 3-[(3-methoxyphenyl)amino]-5,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclohexen-1-one, 3-[(3-methoxyphenyl)amino]-5,5-dimethyl-(50685-32-0)
• EPA Substance Registry System: 2-Cyclohexen-1-one, 3-[(3-methoxyphenyl)amino]-5,5-dimethyl-(50685-32-0)

Safety Data

• Hazardous Substances Data: 50685-32-0(Hazardous Substances Data)

Upstream product

• 2845-89-8 1-chloro-3-methoxy-benzene 
• 873-95-0 1-amino-5,5-dimethylcyclohexen-3-one 
• 2398-37-0 3-methoxyphenyl bromide 
• 536-90-3 m-Anisidine 
• 126-81-8 dimedone 

Downstream Products

• 1222075-27-5 ethyl 1'-benzyl-6-methoxy-3,3-dimethyl-1,2'-dioxo-5'-phenyl-1',2,2',3,4,10-hexahydro-1H-spiro[acridine-9,3'-pyrrole]-4'-carboxylate 
• 1067646-90-5 1-(3-methoxyphenyl)-6,6-dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione 
• 78150-06-8 3-(3-methoxyanilino)-5,5-dimethyl-2-(N-methyl-N-phenethylamino)methyl-2-cyclohexen-1-one 

Relevant articles and documents

Metal-free syntheses of new azocinesviaaddition reactions of enaminones with acenaphthoquinone followed by oxidative cleavages of the corresponding vicinal diols

A one-pot, clean and green procedure is described for the syntheses of new azocine derivativesviaaddition reactions of enaminones with acenaphthoquinone followed by periodic acid-mediated oxidative cleavages of the corresponding vicinal diols. Various derivatives of azocine were prepared and well characterized. The excellent yields, simple synthesis procedure, lack of a need to carry out any tedious work-up and column chromatography, metal-free catalysis, and mild reaction conditions are important features of this protocol.

FeCl3-Catalyzed Combinatorial Synthesis of Functionalized Spiro[Indolo-3,10′-indeno [1,2- b ]quinolin]-trione Derivatives

An efficient, inexpensive, environmentally friendly and high yield one-pot route to new spiro[indolo-3,10′-indeno [1,2-b]quinolin]-trione derivatives has been developed, involving three-component reaction of enaminones, N-substituted isatins and Indane-1,3-dione catalyzed by FeCl3. The approach to this spiro-heterocycle is noteworthy because it results in the formation of three new σ (two C-C and one C-N) bonds in a single operation, leading to the construction of novel spiro skeleton. This method works on a large scale in excellent yields.

Palladium-catalyzed coupling of vinylogous amides with aryl halides: Applications to the synthesis of heterocycles

Described herein is the first example of the palladium-catalyzed coupling of vinylogous amides with aryl bromides and chlorides. The scope of this reaction with respect to the aryl component is investigated. Additionally, a tandem reaction sequence in which the above coupling is followed by an intramolecular Heck reaction is presented. These reactions can be applied to high-yielding, one-pot syntheses of nitrogen-containing heterocycles.