5069-80-7

Basic information

• Product Name: 6-(propylsulfanyl)-5H-purin-2-amine
• CAS NO: 5069-80-7
• Molecular Formula: C₈H₁₁N₅S
• Molecular Weight: 209.2714
• Mol File: 5069-80-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 362.4°C at 760 mmHg
• Flash Point: 173°C
• Density: 1.56g/cm³
• Vapor Pressure: 1.94E-05mmHg at 25°C
• Refractive Index: 1.78
• CAS DataBase Reference: 6-(propylsulfanyl)-5H-purin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(propylsulfanyl)-5H-purin-2-amine(5069-80-7)
• EPA Substance Registry System: 6-(propylsulfanyl)-5H-purin-2-amine(5069-80-7)

Safety Data

• Hazardous Substances Data: 5069-80-7(Hazardous Substances Data)

Upstream product

• 107-08-4 1-iodo-propane 
• 154985-75-8 6-thioguanine 

Downstream Products

• 565473-09-8 2-amino-9-benzyl-6-propylthiopurine 

Relevant articles and documents

Efficient synthesis of 2,9-disubstituted 8-hydroxyadenine derivatives

An efficient and general method for the synthesis of 2,9-disubstituted 8-hydroxyadenines, which are expected to have various biological activities, was realized. 5-amino-4-cyano-2-hydroxyimidazoles(1) were prepared from aminomalononitrile and isocyanates as key intermediates. The condensation of 1a with amidines, imidates, guanidine, urea and thioureas afforded 8-hydroxyadenines (2-6) possessing various substituents at the 2-position. Furthermore, selective alkylation of 2-amino- and 2-hydroxyadenines (4 and 6) successively proceeded to give the corresponding 2-alkylamino- and 2-alkoxyadenines (5 and 7), respectively. 2-Alkythioadenines (15) were prepared by an analogous reaction of 1a with benzoyl isothiocyanate and subsequent S-alkylation. The imidazoles 1 are most useful intermediated for the synthesis of 8-hydroxyadenine derivatives.