50739-30-5

Basic information

• Product Name: 2-BENZYL-THIAZOLIDINE-4-CARBOXYLIC ACID
• Synonyms: 2-BENZYL-THIAZOLIDINE-4-CARBOXYLIC ACID;2-(PHENYLMETHYL)-4-THIAZOLIDINECARBOXYLIC ACID
• CAS NO: 50739-30-5
• Molecular Formula: C₁₁H₁₃NO₂S
• Molecular Weight: 223.29142
• Mol File: 50739-30-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 429.4°C at 760 mmHg
• Flash Point: 213.5°C
• Appearance: /Solid
• Density: 1.277g/cm³
• Vapor Pressure: 3.9E-08mmHg at 25°C
• Refractive Index: 1.61
• CAS DataBase Reference: 2-BENZYL-THIAZOLIDINE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BENZYL-THIAZOLIDINE-4-CARBOXYLIC ACID(50739-30-5)
• EPA Substance Registry System: 2-BENZYL-THIAZOLIDINE-4-CARBOXYLIC ACID(50739-30-5)

Safety Data

• Hazardous Substances Data: 50739-30-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H13NO2S/c13-11(14)9-7-15-10(12-9)6-8-4-2-1-3-5-8/h1-5,9-10,12H,6-7H2,(H,13,14)/t9-,10?/m1/s1

Upstream product

• 59216-85-2 α-formyl phenyl acetic acid 
• 52-89-1 l-cysteine hydrochloride 
• 29969-69-5 3,3-diethoxy-2-phenyl-propionic acid 
• 52-90-4 L-Cysteine 
• 122-78-1 phenylacetaldehyde 

Downstream Products

• 1430843-66-5 dimethyl 3-benzyl-5-methyl-6-trifluoromethyl-3H-pyrrolizine-1,2-dicarboxylate 
• 1430843-67-6 dimethyl 5-benzyl-1-trifluoromethyl-5,8-dihydroindolizine-6,7-dicarboxylate 
• 1430843-65-4 2-methyl-1-styryl-3-trifluoromethyl-1H-pyrrole 
• 1430843-64-3 C₁₄H₁₂F₃N 
• 1430843-63-2 3-benzyl-7-trifluoromethyl-1H,3H-pyrrolo[1,2-c]thiazole-2,2-dioxide 
• 1430843-61-0 (2R,4R)-2-benzyl-3-[(E)-4,4,4-trifluoro-3-oxobut-1-enyl]thiazolidine-4-carboxylic acid 
• 1041643-83-7 C₁₆H₂₁NO₄S 
• 864236-24-8 dimethyl 3-benzyl-5-methyl-1H,3H-pyrrolo[1,2-c]thiazole-6,7-dicarboxylate-2,2-dioxide 
• 864236-38-4 dimethyl 2,5-dimethyl-1-styryl-1H-pyrrole-3,4-dicarboxylate 
• 864236-19-1 dimethyl 3-benzyl-5-methyl-1H,3H-pyrrolo[1,2-c]thiazole-6,7-dicarboxylate 

Relevant articles and documents

Discovery of cysteine and its derivatives as novel antiviral and antifungal agents

Based on the structure of the natural product cysteine, a series of thiazolidine-4-carboxylic acids were designed and synthesized. All target compounds bearing thiazolidine-4-carboxylic acid were characterized by1 H-NMR,13 C-NMR, and

Synthesis and antiproliferative activity of imidazole and imidazoline analogs for melanoma

We have previously reported substituted 2-aryl-thiazolidine-4-carboxylic acid amides as potent and selective antiproliferative agents for melanoma. To understand the importance of the thiazolidine ring and to reduce potential complications associated with the two chiral centers, we designed and synthesized sets of new analogs by modifying this ring. These new analogs were tested in two melanoma cell lines and fibroblast cells (negative controls). Compared with the older analogs containing the thiazolidine ring, these new analogs have lower potency in general, but some of these analogs still have very good selectivity. These structure-activity studies indicated that the thiazolidine ring is very critical for the activity for these series of compounds.