50790-26-6

Basic information

• Product Name: Propanedioic acid, phenyl-2-propenyl-, diethyl ester
• Synonyms: Allyl-phenyl-malonsaeure-diaethylester;diethyl allylphenylmalonate;allyl-phenyl-malonic acid diethyl ester;Propanedioic acid,phenyl-2-propenyl-,diethyl ester;2-Phenyl-2-allyl-ethylmalonat;diethyl-2-phenyl-2-allyl-malonate
• CAS NO: 50790-26-6
• Molecular Formula: C16H20O4
• Molecular Weight: 276.332
• Mol File: 50790-26-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, phenyl-2-propenyl-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, phenyl-2-propenyl-, diethyl ester(50790-26-6)
• EPA Substance Registry System: Propanedioic acid, phenyl-2-propenyl-, diethyl ester(50790-26-6)

Safety Data

• Hazardous Substances Data: 50790-26-6(Hazardous Substances Data)

Usage

Description

Propanedioic acid, phenyl-2-propenyl-, diethyl ester, also known as Diethyl 2-allyl-2-phenylmalonate, is a chemical compound that serves as an intermediate in the synthesis of various pharmaceuticals. It is characterized by its ester functional group and its ability to form a key component in the production of certain drugs.

Uses

Used in Pharmaceutical Industry:
Propanedioic acid, phenyl-2-propenyl-, diethyl ester is used as an intermediate in the synthesis of Alphenal, which is a Barbituric Acid (B118650) derivative. Alphenal possesses anti-convulsive properties and is classified as a controlled substance due to its potential for misuse and dependence.
As an intermediate in the synthesis of Alphenal, Propanedioic acid, phenyl-2-propenyl-, diethyl ester plays a crucial role in the development of medications aimed at treating convulsive disorders and other related conditions. Its involvement in the production of a controlled substance highlights the importance of its regulated use and the need for careful monitoring in the pharmaceutical industry.

Upstream product

• 101-97-3 Ethyl 2-phenylethanoate 
• 90-27-7 2-Phenylbutyric acid 
• 106-95-6 allyl bromide 
• 83-13-6 diethyl 2-phenylmalonate 
• 107-05-1 3-chloroprop-1-ene 
• 556-56-9 allyl iodid 
• 28744-77-6 sodium diethyl-2-phenylmalonate 

Downstream Products

• 1575-70-8 2-phenyl-pent-4-enoic acid 
• 100519-19-5 allyl-phenyl-malonic acid 
• 83-13-6 diethyl 2-phenylmalonate 
• 13395-46-5 2-phenyl-pent-4-enoic acid-(2-diethylamino-ethyl ester) 
• 79835-78-2 5-allyl-5-phenyl-2-thio-barbituric acid 
• 19846-06-1 phenyl-propyl-malonic acid diethyl ester 
• 109689-77-2 2-phenyl-pent-4-enoic acid-(2-piperidino-ethyl ester) 
• 41921-35-1 2-Allyl-2-phenyl-propane-1,3-diol 

Relevant articles and documents

Aryltrifluoromethylative cyclization of unactivated alkenes by the use of PhICF3Cl under catalyst-free conditions

A concise and catalyst-free aryltrifluoromethylative cyclization of unactivated alkenes has been developed herein. The use of PhICF3Cl as a powerful trifluoromethylating agent allows easy transformations. A set of trifluoroethylated carbocycles and aza-hereocycles were efficiently synthesized in good yield and selectivity. A broad substrate scope, mild reaction conditions, and easy operation would make this method well-suited for applications.

Pd-catalyzed α-allylation of 2-phenylpropanal and other carbonyl compounds with allyl alcohol and allyl acetates/carbonates in ionic liquids

The successful Pd-catalysed allylation of 2-phenylpropanal with allyl alcohol in ionic liquid is described and thus a simplier reaction composition catalytic system than in THF is possible. On the other hand, the Pd-catalyzed α-allylation of the same substrate with allyl acetate or allyl ethyl carbonate is proceeding nicely in ionic liquids. Allylation of different carbonyl derivatives was studied and it was found that the reaction is restricted to carbonyl derivatives from which a carbanion stabilized by an adjacent aromatic ring can be formed.

Insecticidal esters of substituted furan methanol

Substituted acetate compounds represented by the formula STR1 which are useful as pesticides and pesticidal composition containing the substituted acetate compounds as active ingredients, as well as processes for preparing the compounds and the compositio