5089-33-8 Usage
Description
4-Bromo-N,N-bis(trimethylsilyl)aniline is an N-protected aryl reagent that plays a crucial role in the synthesis of various organic compounds and materials. Its unique structure allows for versatile applications in chemical reactions and material development.
Uses
Used in Photodynamic Therapy Applications:
4-Bromo-N,N-bis(trimethylsilyl)aniline is used as a key intermediate in the synthesis of hydrophilic conjugated porphyrin dimers, which are employed for one-photon and two-photon photodynamic therapy. These porphyrin dimers exhibit enhanced solubility and biocompatibility, making them suitable for effective light-induced therapeutic treatments.
Used in Polymer Synthesis:
In the polymer industry, 4-Bromo-N,N-bis(trimethylsilyl)aniline serves as a building block for the synthesis of functionalized organometallic polymers, such as poly(ferrocenylsilane). These polymers possess unique electronic, optical, and mechanical properties, making them suitable for various applications, including electronic devices, sensors, and actuators.
Used in Borylation Chemistry:
4-Bromo-N,N-bis(trimethylsilyl)aniline is utilized as a precursor for the synthesis of borylanilines, such as 4-(dimesitylboryl)aniline and 4-(dimesitylboryl)-3,5-dimethylaniline. These borylanines are valuable intermediates in organic synthesis and can be used to construct complex organic molecules with potential applications in pharmaceuticals, agrochemicals, and materials science.
Used in Polymer Science:
In the field of polymer science, 4-Bromo-N,N-bis(trimethylsilyl)aniline is employed as a monomer in the synthesis of silicon-containing oligomeric poly(imido-amides) (PIAs). These PIAs exhibit excellent thermal stability, mechanical properties, and chemical resistance, making them suitable for high-performance applications, such as aerospace, automotive, and electronics industries.
Check Digit Verification of cas no
The CAS Registry Mumber 5089-33-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,0,8 and 9 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 5089-33:
(6*5)+(5*0)+(4*8)+(3*9)+(2*3)+(1*3)=98
98 % 10 = 8
So 5089-33-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H22BrNSi2/c1-15(2,3)14(16(4,5)6)12-9-7-11(13)8-10-12/h7-10H,1-6H3
5089-33-8Relevant articles and documents
Synthesis and Characterization of (Disilylanilino)Phosphines
Devulapalli, Pradeep,Wang, Bin,Neilson, Robert H.
, p. 2154 - 2163 (2015)
(Graphical Abstract) The disilyl(4-bromo)aniline (Me3Si)2NC6H4Br (A) readily undergoes metal-halogen exchange to give the reactive organolithium derivative (Me3Si)2NC6H4/su
POLYAMIC ACID PRECURSOR COMPOUND INCLUDING SILICON, POLYAMIC ACID AND ORGANIC INORGANIC HYBRID POLYIMIDE FILM
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Paragraph 0175-0179, (2018/04/14)
Provided is a polyamic acid precursor compound including silicon, which is represented by chemical formula 1. In chemical formula 1, X and R_1 are the same as defined in the specification. One embodiment of the present invention provides the polyamic acid precursor compound including silicon, which is excellent in light transmittance and can be induced to a polyamic acid having excellent heat resistance and high temperature durability.COPYRIGHT KIPO 2018
Synthesis of potential antitubercular and antimicrobial s-triazine-based scaffolds via Suzuki cross-coupling reaction
Patel, Amit B.,Patel, Rahul V.,Kumari, Premlata,Rajani, Dhanji P.,Chikhalia, Kishor H.
, p. 367 - 381 (2013/03/13)
Two series of bis(3,5-dimethylpiperidinyl)-1,3,5-triazinyl)-N-(phenyl/ benzothiazolyl)-acetamides were synthesized so as to investigate their antimicrobial and antimycobacterial actions. Intermediate 4-(4,6-bis(3,5- dimethylpiperidin-1-yl)-1,3,5-triazin-2-yl)aniline was synthesized by palladium-catalyzed Suzuki cross-coupling reaction to furnish C-C bond formation to s-triazine ring. Pharmacological screening against eight bacteria (S. aureus, B. cereus, E. coli, P. aeruginosa, K. pneumoniae, S. typhi, P. vulgaris, and S. flexneri), four fungi (A. niger, A. fumigatus, A. clavatus, and C. albicans), and Mycobacterium tuberculosis H37Rv was examined and the effects of various substituents on biological profiles (MIC, 1.56-50 μg/mL) of final analogues were investigated. Four (8c, 8i, 9d, 9j) of the final analogues displayed antimycobacterial activity (3.12-6.25 μg/mL) equipotent to standard drugs.