509112-67-8Relevant articles and documents
Design, synthesis and biological screening of new 4-thiazolidinone derivatives with promising COX-2 selectivity, anti-inflammatory activity and gastric safety profile
Abdellatif, Khaled R.A.,Abdelgawad, Mohamed A.,Elshemy, Heba A.H.,Alsayed, Shahinda S.R.
, p. 1 - 12 (2015/11/18)
Two series of new thiazolidin-4-one derivatives 4a-c and 8a-e were designed and prepared. All the synthesized compounds were evaluated for their in vitro COX-2 selectivity and anti-inflammatory activity in vivo. Compounds 8c and 8d showed the best overall