51-01-4

Basic information

• Product Name: 2,4-bis(acetyloxy)benzoic acid
• Synonyms: 2,4-Diacetoxybenzoic acid; benzoic acid, 2,4-bis(acetyloxy)-
• CAS NO: 51-01-4
• Molecular Formula: C₁₁H₁₀O₆
• Molecular Weight: 238.1935
• Mol File: 51-01-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 383.3°C at 760 mmHg
• Flash Point: 149.1°C
• Density: 1.344g/cm³
• Vapor Pressure: 1.47E-06mmHg at 25°C
• Refractive Index: 1.543
• CAS DataBase Reference: 2,4-bis(acetyloxy)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-bis(acetyloxy)benzoic acid(51-01-4)
• EPA Substance Registry System: 2,4-bis(acetyloxy)benzoic acid(51-01-4)

Safety Data

• Hazardous Substances Data: 51-01-4(Hazardous Substances Data)

Usage

General Description

2,4-bis(acetyloxy)benzoic acid, also known as aspirin, is a chemical compound that is commonly used as a pain reliever and fever reducer. It belongs to the class of medications known as nonsteroidal anti-inflammatory drugs (NSAIDs), and works by inhibiting the production of certain chemicals in the body that cause inflammation, pain, and fever. Aspirin is also used to prevent heart attacks and strokes in individuals at high risk, and it may also have anti-cancer properties. However, it can cause side effects such as stomach irritation, bleeding, and allergic reactions, and should be used with caution in certain populations, such as those with asthma or bleeding disorders. Overall, 2,4-bis(acetyloxy)benzoic acid is a widely used and important medication with various therapeutic effects and potential risks.

Upstream product

• 108-46-3 recorcinol 
• 108-24-7 acetic anhydride 
• 18393-49-2 3',4',7-trihydroxyflavylium chloride 
• 39972-59-3 2,3',4,4'-Tetrahydroxy-chalkon 
• 1222-48-6 7-hydroxy-4'-methoxyflavylium chloride 
• 89-86-1 4-hydroxysalicylic acid 
• 75-36-5 acetyl chloride 
• 89494-26-8 2,4-diacetoxy-4'-methoxy-chalcone 
• 2150-11-0 3',4',7-trihydroxyflavone 
• 95-01-2 2,4-Dihydroxybenzaldehyde 

Downstream Products

• 1245209-67-9 2,4-diacetoxybenzoyl azide 
• 1035951-38-2 Acetic acid 5-acetoxy-2-ethoxycarbonyloxycarbonyl-phenyl ester 
• 77008-83-4 2,4-Diacetoxybenzoesaeure-4-nitrophenylester 
• 84388-74-9 2,4-Diacetoxybenzoesaeure-N-hydroxysuccinimidester 
• 50740-12-0 2,4-diacetoxybenzoyl chloride 
• 855875-90-0 3,5-diacetyl-2,4-dihydroxy-benzoic acid 
• 91485-08-4 2-Acetoxy-4-hydroxybenzoesaeure 
• 3147-44-2 2,4-dihydroxy-N-phenylbenzamide 
• 91-52-1 2,4 dimethoxybenzoic acid 
• 905584-39-6 2,4-diacetoxy-benzoic acid 4-[bis-(4-hydroxy-2-oxo-2H-chromen-3-yl)-methyl]-phenyl ester 
• 55981-14-1 Acetic acid 5-acetoxy-2-(5-nitro-thiazol-2-ylcarbamoyl)-phenyl ester 

Relevant articles and documents

Improved compsn. antiallergic habitus

PROBLEM TO BE SOLVED: To provide a composition for ameliorating allergic constitution naturally ingestible in daily life. SOLUTION: The composition for ameliorating the allergic constitution comprises a galactooligosaccharide as a main ingredient. Furthermore, a food and drink uses the composition. Since the galactooligosaccharide is already widely used in heath-oriented foods such as a specific food for health and is a material in which the safety is sufficiently established, the galactooligosaccharide is naturally ingestible over a long period in the daily life. COPYRIGHT: (C)2007,JPOandINPIT

Synergistically acting compositions for selectively combating tumor tissue

According to the invention, compositions are made available which have a strong cytotoxic effect which is largely selective on tumor tissue. The invention is based on the fact that certain benzoic acid derivatives have a strong synergistic effect as a mixture and destroy cancer cells selectively in a pH range of 7 or below, such as from 6.5 to 7.

Cobalt(II)-Catalyzed Reaction of Aldehydes with Acetic Anhydride under an Oxygen Atmosphere: Scope and Mechanism

The reaction of aldehydes with acetic anhydride in the presence of catalytic cobalt(II) chloride under an oxygen atmosphere at ambient temperature is dependent upon the reaction medium.Aliphatic aldehydes react in acetonitrile to give 1,2-diones whereas the aromatic aldehydes are acylated to yield the corresponding acylals.On the other hand, carboxylic acids are obtained from aliphatic and aromatic aldehydes by conducting the reaction in dichloroethane or benzene.Cobalt(II) chloride in acetonitrile catalyzes the conversion of aliphatic aldehydes to the correspondinganhydrides in the absence of acetic anhydride whereas aromatic aldehydes remain largely unaffected under these conditions.A preliminary mechanistic study in three different solvents (i.e. acetonitrile, dichloroethane, and DMF) has revealed that in acetonitrile and in the presence of acetic anhydride, aliphatic aldehydes behave differently than aromatic aldehydes.Some trapping experiments using methyl acrylate and stilbene have been conducted to demonstrate the occurence of an acyl cobalt and peroxyacyl cobalt intermediate during these reactions.