51-56-9

Basic information

• Product Name: alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide
• Synonyms: alpha-hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide;MANDELYTROPINE HYDROBROMIDE;(+/-)-HOMATROPINE HYDROBROMIDE;HOMATROPINE HYDROBROMIDE;DL-HOMATROPINE HYDROBROMIDE;(+-)-homatropinebromide;1-alpha-h,5-alpha-h-tropan-3-alpha-ol,mandelate(ester),hydrobromide;alpha-hydroxy-benzeneaceticaci8-methyl-8-azabicyclo(3.2.1)oct-3-yleste
• CAS NO: 51-56-9
• Molecular Formula: BrH*C₁₆H₂₁NO₃
• Molecular Weight: 356.25
• EINECS: 200-105-3
• Product Categories: Miscellaneous Natural Products;Alkaloids;Biochemistry;Tropane Alkaloids;Acetylcholine receptor;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;ISOPTO
• Mol File: 51-56-9.mol
• Article Data: 0

Chemical Properties

• Melting Point: 214-217 °C
• Boiling Point: 434.9 °C at 760 mmHg
• Flash Point: 216.8 °C
• Appearance: /
• Density: 1.21g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Storage Temp.: 2-8°C
• Solubility: Freely soluble in water, sparingly soluble in alcohol.
• Water Solubility: soluble
• Merck: 14,4730
• CAS DataBase Reference: alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide(CAS DataBase Reference)
• NIST Chemistry Reference: alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide(51-56-9)
• EPA Substance Registry System: alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide(51-56-9)

Safety Data

• Hazard Codes: T
• Statements: 23/24/25
• Safety Statements: 45-24/25-22
• RIDADR: 1544
• WGK Germany: 3
• RTECS: YM5602000
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 51-56-9(Hazardous Substances Data)

Usage

Description

alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide is a complex organic compound with a unique chemical structure. It is characterized by its ester and hydrobromide functional groups, which contribute to its chemical properties and potential applications.

Uses

Used in Pharmaceutical Industry:
alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide is used as an active pharmaceutical ingredient for the development of new drugs targeting various medical conditions. Its unique chemical structure allows for potential interactions with specific biological targets, making it a promising candidate for drug discovery and development.
Used in Chemical Research:
alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide is also used as a research tool in the field of organic chemistry, where it can be employed to study the properties and reactivity of ester and hydrobromide functional groups. It can be used to investigate various chemical reactions and mechanisms, contributing to the advancement of chemical knowledge.
Used in Analytical Chemistry:
alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide can be utilized as a reference compound or standard in analytical chemistry. Its unique structure and properties make it suitable for calibration and quality control purposes in various analytical techniques, such as chromatography and spectroscopy.
Used in Material Science:
alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide may also find applications in the field of material science, where its unique chemical structure could be exploited to develop new materials with specific properties. These materials could have potential uses in various industries, such as electronics, aerospace, or automotive.

Clinical Use

Homatropine hydrobromide is used topically to paralyzethe ciliary structure of the eye (cycloplegia) and to effectmydriasis. It behaves very much like atropine but is weakerand less toxic. In the eye, it acts more rapidly but less persistentlythan atropine. Dilation of the pupil takes place inabout 15 to 20 minutes, and the action subsides in about24 hours. By using a miotic, such as physostigmine, it ispossible to restore the pupil to normality in a few hours.

InChI:InChI:1S/C16H21NO3.BrH/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11;/h2-6,12-15,18H,7-10H2,1H3;1H

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