51043-64-2

Basic information

• Product Name: diethyl N-<4-<(cyanomethyl)amino>benzoyl>-L-glutamate
• Synonyms: diethyl N-<4-<(cyanomethyl)amino>benzoyl>-L-glutamate
• CAS NO: 51043-64-2
• Molecular Weight: 361.398
• Mol File: 51043-64-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: diethyl N-<4-<(cyanomethyl)amino>benzoyl>-L-glutamate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl N-<4-<(cyanomethyl)amino>benzoyl>-L-glutamate(51043-64-2)
• EPA Substance Registry System: diethyl N-<4-<(cyanomethyl)amino>benzoyl>-L-glutamate(51043-64-2)

Safety Data

• Hazardous Substances Data: 51043-64-2(Hazardous Substances Data)

Upstream product

• 13726-52-8 diethyl N-(p-aminobenzoyl)-L-glutamate 
• 590-17-0 cyanomethyl bromide 
• 107-14-2 chloroacetonitrile 
• 50-00-0 formaldehyd 

Downstream Products

• 80014-95-5 (S)-2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-carbamoylmethyl-amino]-benzoylamino}-pentanedioic acid 
• 80015-08-3 diethyl N-<4--N-(cyanomethyl)amino>benzoyl>-L-glutamate 

Relevant articles and documents

Synthesis of 7 azafolic acid (1)

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Folate analogues. 21. Synthesis and antifolate and antitumor activities of N10-(cyanomethyl)-5,8-dideazafolic acid

A close analogue of the antileukemic agent 5,8-dideaza-N10 propargylfolic acid (2) was synthesized by replacing the propargyl moiety of 2 with a cyanomethyl group. This compound, N10-(cyanomethyl)-5,8-dideazafolic acid (3), was evalu