51043-75-5Relevant articles and documents
ARYL ANNULATED MACROCYCLIC INDOLE DERIVATIVES
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Page/Page column 168-169, (2019/06/05)
The present invention relates to aryl annulated macrocyclic indole derivatives of general formula (I): in which R1, R2, R3, R4, R5, R6, A and L are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.
Keratinocyte growth inhibitors and hydroxamic acid derivatives
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Page 20, (2010/02/06)
This invention relates to a keratinocyte-proliferation inhibitor comprising as active ingredient a compound having an activity of inhibiting the solubilization of heparin-binding EGF-like growth factor bound to cell membranes and a compound of the formula (I); or pharmaceutically acceptable salt thereof, wherein R1, R2, R3 are hydrogen atom or alkyl and X is substituted benzene or the like.
-Methyl Functionalization of Electron-Poor Heterocycles: Free Radical Chlorination
Newkome, George R.,Kiefer, Garry E.,Yuan-Jiao Xia,Gupta, Vinod K.
, p. 676 - 679 (2007/10/02)
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