511261-60-2Relevant articles and documents
Design and synthesis of 6-amino-5-oxo-1,2,3,5-tetrahydro-3-indolizinecarboxylic acids as β-sheet peptidomimetics
Zhang, Xiaojun,Schmitt, Aaron C.,Decicco, Carl P.
, p. 9663 - 9666 (2007/10/03)
6-Amino-5-oxo-1,2,3,5-tetrahydro-3-indolizinecarboxylic acid was designed as a novel scaffold that can effectively mimic the extended conformation of a peptide. The key reaction in the synthesis of the scaffold involved a [3+2]-cycloaddition of a dicarbon