511261-64-6

Basic information

• Product Name: (1R,3S)-8-Acetyl-1-benzyloxycarbonylamino-1-methyl-5-oxo-6-(toluene-3-sulfonylamino)-1,2,3,5-tetrahydro-indolizine-3-carboxylic acid methyl ester
• Synonyms: (1R,3S)-8-Acetyl-1-benzyloxycarbonylamino-1-methyl-5-oxo-6-(toluene-3-sulfonylamino)-1,2,3,5-tetrahydro-indolizine-3-carboxylic acid methyl ester
• CAS NO: 511261-64-6
• Molecular Weight: 567.62
• Mol File: 511261-64-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,3S)-8-Acetyl-1-benzyloxycarbonylamino-1-methyl-5-oxo-6-(toluene-3-sulfonylamino)-1,2,3,5-tetrahydro-indolizine-3-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,3S)-8-Acetyl-1-benzyloxycarbonylamino-1-methyl-5-oxo-6-(toluene-3-sulfonylamino)-1,2,3,5-tetrahydro-indolizine-3-carboxylic acid methyl ester(511261-64-6)
• EPA Substance Registry System: (1R,3S)-8-Acetyl-1-benzyloxycarbonylamino-1-methyl-5-oxo-6-(toluene-3-sulfonylamino)-1,2,3,5-tetrahydro-indolizine-3-carboxylic acid methyl ester(511261-64-6)

Safety Data

• Hazardous Substances Data: 511261-64-6(Hazardous Substances Data)

Upstream product

• 108963-96-8 (S)-1-tert-butoxycarbonyl-5-methoxycarbonyl-pyrrolidin-2-one 
• 511261-58-8 (1R,3S)-8-Acetyl-1-benzyloxycarbonylamino-6-tert-butoxycarbonylamino-1-methyl-5-oxo-1,2,3,5-tetrahydro-indolizine-3-carboxylic acid methyl ester 
• 511261-68-0 (1R,3S)-8-Acetyl-6-hydroxy-1-methyl-5-oxo-1,2,3,5,6,7-hexahydro-indolizine-1,3,6-tricarboxylic acid 1-benzyl ester 6-tert-butyl ester 3-methyl ester 
• 511261-56-6 (1R,3S)-8-Acetyl-6-tert-butoxycarbonylamino-1-methyl-5-oxo-1,2,3,5-tetrahydro-indolizine-1,3-dicarboxylic acid 1-benzyl ester 3-methyl ester 
• 511261-72-6 (1R,3S)-8-Acetyl-1-methyl-5-oxo-1,2,3,5-tetrahydro-indolizine-1,3,6-tricarboxylic acid 1-benzyl ester 6-tert-butyl ester 3-methyl ester 
• 511261-66-8 (2S,4R)-1-(2-tert-Butoxycarbonyl-2-diazo-acetyl)-4-methyl-5-oxo-pyrrolidine-2,4-dicarboxylic acid 4-benzyl ester 2-methyl ester 
• 511261-52-2 (2S,4R)-4-Methyl-5-oxo-pyrrolidine-1,2,4-tricarboxylic acid 4-benzyl ester 1-tert-butyl ester 2-methyl ester 
• 511261-54-4 (2S,4R)-4-Methyl-5-oxo-pyrrolidine-2,4-dicarboxylic acid 4-benzyl ester 2-methyl ester 
• 511261-50-0 O₁-tert-butyl O₂-methyl (2S)-4-methyl-5-oxo-pyrrolidine-1,2-dicarboxylate 
• 1899-93-0 3-methylphenylsulfonyl chloride 

Relevant articles and documents

Design and synthesis of 6-amino-5-oxo-1,2,3,5-tetrahydro-3-indolizinecarboxylic acids as β-sheet peptidomimetics

6-Amino-5-oxo-1,2,3,5-tetrahydro-3-indolizinecarboxylic acid was designed as a novel scaffold that can effectively mimic the extended conformation of a peptide. The key reaction in the synthesis of the scaffold involved a [3+2]-cycloaddition of a dicarbon