5116-31-4Relevant articles and documents
An improved procedure for nucleoside synthesis using glycosyl trifluoroacetimidates as donors
Liao, Jinxi,Sun, Jiansong,Yu, Biao
, p. 1034 - 1038 (2009)
Using glycosyl trifluoroacetimidates as donors and nitromethane (or acetonitrile) as solvent, silylation and subsequent glycosylation were realized in a 'one-pot' procedure to provide the corresponding nucleosides derivatives in high yields.{A figure is p
Synthesis of pyridinone ribonucleoside 3'-O-phosphoramidites and their incorporation into oligoribonucleotides
Matulic-Adamic,Gonzalez,Usman,Beigelman
, p. 373 - 378 (2007/10/03)
Protected pyridin-2- and pyridin-4-one ribonucleosides 3 and 9 were synthesized using a one-pot reaction of silylated bases with 1-O-acetyl-tri-O-benzoyl-β-D-ribofuranose (2) in the presence of CF3SO3SiMe3. The nucleosides were converted in 4 steps into 3'-O-phosphoramidites 7 and 11 which were incorporated into hammerhead ribozyme substrates using solid-phase phosphoramidite chemistry.