5117-16-8

Basic information

• Product Name: 1,1-DIMETHYL-2-SELENOUREA
• Synonyms: N,N-DIMETHYL-2-SELENOUREA;asym-Dimethylselenium urea;1,1-DIMETHYL-2-SELENOUREA;n,n-dimethyl-selenoure;N,N-Dimethylselenourea,97%;1,1-Dimethylselenourea;1,1-Dimethyl-2-selenourea,97%;1,1-Dimethyl-2-selenourea 97%
• CAS NO: 5117-16-8
• Molecular Formula: C₃H₈N₂Se
• Molecular Weight: 151.07
• EINECS: 225-854-3
• Product Categories: Building Blocks;Organic Building Blocks;Selenium Compounds;organoselenides
• Mol File: 5117-16-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 172-174 °C(lit.)
• Boiling Point: 177.2±23.0 °C(Predicted)
• Appearance: /solid
• Storage Temp.: 0-6°C
• CAS DataBase Reference: 1,1-DIMETHYL-2-SELENOUREA(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-DIMETHYL-2-SELENOUREA(5117-16-8)
• EPA Substance Registry System: 1,1-DIMETHYL-2-SELENOUREA(5117-16-8)

Safety Data

• Hazard Codes: T,N
• Statements: 23/25-33-50/53
• Safety Statements: 20/21-28-45-60-61-50
• RIDADR: UN 3283 6.1/PG 2
• WGK Germany: 3
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 5117-16-8(Hazardous Substances Data)

Usage

Uses

1,1-Dimethyl-2-selenourea was used as precursor to synthesize CdSe quantum dots in aqueous solution under simultaneous illumination with a diode-pumped solid state green laser and a Xe-Hg lamp.

General Description

One-electron oxidation of 1,1-dimethyl-2-selenourea (1,1′-dimethyl-2-selenourea) by hydroxyl radicals, one-electron-specific oxidants, was studied using pulse radiolysis technique.

InChI:InChI=1/C3H7N2Se/c1-5(2)3(4)6/h4H,1-2H3

Upstream product

• 1467-79-4 NCNMe₂ 

Downstream Products

• 1384463-45-9 4-(2-(dimethylamino)-1,3-selenazol-4-yl)benzonitrile 
• 154437-05-5 N,N-dimethyl-4-phenyl-1,3-selenazol-2-amine 
• 5533-45-9 2-dimethylamino-5-phenyl-selenazol-4-one 

Relevant articles and documents

Inhibition of tyrosinase activity by N,N-unsubstituted selenourea derivatives

This study investigated inhibitory effects of N,N-unsubstituted selenourea derivatives on tyrosinase activity. Three types of N,N-unsubstituted selenoureas derivatives exhibited inhibitory effect on dopa (3,4-dihydroxyphenylalanine) oxidase activity of mushroom tyrosinase. Compound D at a concentration of 200/M exhibited 55.5% of inhibition on dopa oxidase activity of mushroom tyrosinase. This inhibitory effect was higher than that of kojic acid (39.4%), a well known tyrosinase inhibitor. Moreover, the compound D identified as a noncompetitive inhibitor by Lineweaver-Burk plot analysis. In addition, compound D also inhibited the melanin production in melan-a cells.

A Simple Route to N,N-Disubstituted Selenoureas from N,N-Disubstituted Cyanamides

N,N-Disubstituted selenoureas 4 can be obtained in satisfactory yields by addition of an acid to a mixture of freshly prepared sodium selenide and N,N-disubstituted cyanamides 5.

Preparation and characterisation of N,N-disubstituted 2-amino-selenazoles

As a result of checking suited methods for preparing N,N-disubstituted 2-amino-selenazoles 14 as a nearly unknown class of highly reactive selenazoles a simple route starting from N,N-disubstituted selenoureas 12 has been elaborated and used for the synthesis of a series of these compounds. The necessary selenium-containing starting compounds 12 are available from N,N-disubstituted cyanamides 18 and hydrogen selenide.