51229-57-3

Basic information

• Product Name: 1-chloro-3-[(phenylsulfonyl)methyl]benzene
• CAS NO: 51229-57-3
• Molecular Formula: C₁₃H₁₁ClO₂S
• Molecular Weight: 266.7432
• Mol File: 51229-57-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 448.5°C at 760 mmHg
• Flash Point: 225°C
• Density: 1.308g/cm³
• Vapor Pressure: 8.19E-08mmHg at 25°C
• Refractive Index: 1.599
• CAS DataBase Reference: 1-chloro-3-[(phenylsulfonyl)methyl]benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-3-[(phenylsulfonyl)methyl]benzene(51229-57-3)
• EPA Substance Registry System: 1-chloro-3-[(phenylsulfonyl)methyl]benzene(51229-57-3)

Safety Data

• Hazardous Substances Data: 51229-57-3(Hazardous Substances Data)

Usage

Explanation

This is the IUPAC name of the compound, indicating the position of the chlorine and sulfonyl groups on the benzene ring.

Explanation

An alternative name for the compound, derived from the tosyl (phenylsulfonyl) group attached to the benzene ring.

Explanation

The compound belongs to a class of organic compounds characterized by the presence of a benzene ring.

Explanation

The molecule consists of a benzene ring with a chlorine atom and a phenylsulfonyl group attached to it.

Explanation

Tosylchlorobenzene is used as a starting material or intermediate in the production of various pharmaceuticals and agrochemicals.

Explanation

The compound is employed as a reagent in various organic synthesis reactions, facilitating the formation of new chemical bonds.

Explanation

Tosylchlorobenzene serves as a precursor, or starting material, for the synthesis of a range of different compounds.

Explanation

The compound can be toxic and may cause skin and eye irritation upon contact, necessitating careful handling and proper safety precautions.

Explanation

Due to its potential toxicity and irritant properties, it is essential to follow safety guidelines and use appropriate protective equipment when working with this chemical.

Class

Aromatic compounds

Structure

Chloro-substituted benzene with a sulfonyl group

Applications

Intermediate in pharmaceuticals and agrochemicals synthesis

Use as a Reagent

Organic synthesis

Precursor

Preparation of various compounds

Toxicity

Potential health hazards

Safety Precautions

Handle with care

Upstream product

• 873-55-2 sodium benzenesulfonate 
• 620-20-2 1-Chloro-3-chloromethyl-benzene 
• 41037-86-9 (α-Jod-3-chlor-benzyl)-phenyl-sulfon 
• 41037-81-4 (α-Brom-3-chlor-benzyl)-phenyl-sulfon 
• 41037-75-6 (α,3-Dichlor-benzyl)-phenyl-sulfon 
• 766-80-3 1-bromomethyl-3-chlorobenzene 

Downstream Products

• 23958-24-9 trans-1,2-bis-(3-chlorophenyl)ethene 
• 20101-53-5 (Z)-1,2-bis(3-chlorophenyl)ethene 

Relevant articles and documents

Nucleophilic reactivities of benzenesulfonyl-substituted carbanions

Kinetics of the reactions of four benzenesulfonyl-stabilized carbanions (1a-d)- with reference electrophiles (quinone methides 2 and diarylcarbenium ions 3) have been determined in dimethyl sulfoxide solution at 20 °C in order to derive the rea