512779-47-4Relevant articles and documents
Synthesis and SAR of 1-hydroxy-1 H -benzo[ d ]imidazol-2(3 H)-ones as inhibitors of d -amino acid oxidase
Berry, James F.,Rais, Rana,Slusher, Barbara S.,Tsukamoto, Takashi,Ferraris, Dana V.,Duvall, Bridget,Hin, Niyada,Alt, Jesse,Thomas, Ajit G.,Rojas, Camilo,Hashimoto, Kenji
supporting information, p. 839 - 843,5 (2020/09/15)
A series of 1-hydroxy-1H-benzo[d]imidazol-2(3H)-ones were synthesized and evaluated for their ability to inhibit human and porcine forms of d-amino acid oxidase (DAAO). The inhibitory potency is largely dependent on the size and position of substituents o
