5128-55-2

Basic information

• Product Name: 3-(4-cyanophenoxy)benzoic acid
• Synonyms: benzoic acid, 3-(4-cyanophenoxy)-
• CAS NO: 5128-55-2
• Molecular Formula: C₉H₁₆O₃
• Molecular Weight: 239.2262
• Mol File: 5128-55-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 444.3°C at 760 mmHg
• Flash Point: 222.5°C
• Density: 1.35g/cm³
• Vapor Pressure: 1.13E-08mmHg at 25°C
• Refractive Index: 1.643
• CAS DataBase Reference: 3-(4-cyanophenoxy)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-cyanophenoxy)benzoic acid(5128-55-2)
• EPA Substance Registry System: 3-(4-cyanophenoxy)benzoic acid(5128-55-2)

Safety Data

• Hazardous Substances Data: 5128-55-2(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 932-51-4 2,5-dimethylcyclohexanone 

Relevant articles and documents

Oxidation of 2-substituted cycloalkanones with cerium(IV) sulfate tetrahydrate in alcohols and acetic acid

The reaction of 2-substituted cycloalkanones with cerium(IV) sulfate tetrahydrate (CS) in alcohols and acetic acid gave the corresponding alkyl esters of oxo acids (80-96%) and oxo acids (78-96%), respectively, by oxidative cleavage of the C(R).C=O bond. In the case of 2-iodocycloalkanones in methanol, the dimethyl ester was obtained in good yield. A treatment of 5α-cholestan-3-one with CS in methanol produced 2-acetal 3-ester of 2,3-seco derivative in good yield. The effects of cerium(IV) and copper(II) salts are also discussed.

N-benzyl indol-3-yl butanoic acid derivatives as cyclooxygenase inhibitors

The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. STR1 The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.