51304-72-4

Basic information

• Product Name: [3-(methylsulfanyl)phenyl]hydrazine
• Synonyms: [3-(methylsulfanyl)phenyl]hydrazine
• CAS NO: 51304-72-4
• Molecular Formula: C₇H₁₀N₂S
• Molecular Weight: 154.2327
• Mol File: 51304-72-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [3-(methylsulfanyl)phenyl]hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: [3-(methylsulfanyl)phenyl]hydrazine(51304-72-4)
• EPA Substance Registry System: [3-(methylsulfanyl)phenyl]hydrazine(51304-72-4)

Safety Data

• Hazardous Substances Data: 51304-72-4(Hazardous Substances Data)

Upstream product

• 4867-37-2 1-chloro-3-methylsulfanylbenzene 
• 1783-81-9 3-methylmercaptoaniline 

Downstream Products

• 629610-35-1 N-[2'-(aminosulfonyl)-1,1'-biphenyl-4-yl]-3-methyl-1-(3-{methyl[(4-methylphenyl)sulfonyl]-sulfinimidoyl}phenyl)-1H-pyrazole-5-carboxamide 
• 629610-19-1 5-methyl-2-(3-methylsulfanyl-phenyl)-2H-pyrazole-3-carboxylic acid (2'-tert-butylsulfamoyl-biphenyl-4-yl)-amide 

Relevant articles and documents

Palladium-catalyzed cross-coupling of aryl chlorides and tosylates with hydrazine

Hydrazine is not a problem anymore: The title transformation is the first reaction to yield aryl hydrazines through the cross-coupling of aryl chlorides and tosylates with hydrazine. An appropriately designed palladium catalyst allows this reaction to proceed rapidly under mild conditions, and with excellent chemoselectivity (see scheme; Ad=adamantyl, Ts=4-toluenesulfonyl).

Carbazole methyl malonates

A process for the preparation of α-methyl-carbazole-2-acetic acids, which comprises reacting an α-methyl-3-oxocyclohexane malonic acid di-lower alkyl ester with a substituted phenylhydrazine, and thereafter sequentially oxidizing and hydrolyzing the reaction product to obtain the desired acid, is described.