5137-38-2

Basic information

• Product Name: Methanone, bis(4-pentylphenyl)-
• CAS NO: 5137-38-2
• Molecular Formula: C23H30O
• Molecular Weight: 322.491
• Mol File: 5137-38-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Methanone, bis(4-pentylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, bis(4-pentylphenyl)-(5137-38-2)
• EPA Substance Registry System: Methanone, bis(4-pentylphenyl)-(5137-38-2)

Safety Data

• Hazardous Substances Data: 5137-38-2(Hazardous Substances Data)

Upstream product

• 51554-95-1 4-pentylbromobenzene 
• 98-86-2 acetophenone 

Downstream Products

• 103100-06-7 <2-Dimethylaminoaethyl>-<4.4'-dipentyl-benzhydryl>-aether 

Relevant articles and documents

One-pot synthesis of diarylmethanones through palladium-catalyzed sequential coupling and aerobic oxidation of aryl bromides with acetophenone as a latent carbonyl donor

A one-pot palladium-catalyzed synthesis of symmetrical and unsymmetrical diarylmethanones using acetophenone and aryl bromides as raw materials has been developed. In this reaction, acetophenone acts as a latent carbonyl donor and two pathways of palladium-catalyzed sequential coupling and aerobic oxidation are identified. The reaction is applicable to a spectrum of substrates and delivers the products in moderate to good yields. This method can be used for the synthesis of ketoprofen, a nonsteroidal anti-inflammatory drug, in a two-step procedure and 45% overall yield.