51420-35-0

Basic information

• Product Name: 3-(ETHYLTHIO)-1H-1,2,4-TRIAZOL-5-AMINE
• Synonyms: ASISCHEM C39063;AKOS BBS-00008022;3-(ETHYLTHIO)-1H-1,2,4-TRIAZOL-5-AMINE;AKOS A1231-1382;AKOS VGYB0000237;1H-1,2,4-triazol-3-amine, 5-(ethylthio)-;5-(ethylthio)-1H-1,2,4-triazol-3-amine;3-(ethylthio)-1H-1,2,4-triazol-5-amine(SALTDATA: FREE)
• CAS NO: 51420-35-0
• Molecular Formula: C₄H₈N₄S
• Molecular Weight: 144.2
• Mol File: 51420-35-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 383.5°C at 760 mmHg
• Flash Point: 185.7°C
• Appearance: /
• Density: 1.36g/cm³
• Vapor Pressure: 4.37E-06mmHg at 25°C
• Refractive Index: 1.622
• CAS DataBase Reference: 3-(ETHYLTHIO)-1H-1,2,4-TRIAZOL-5-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(ETHYLTHIO)-1H-1,2,4-TRIAZOL-5-AMINE(51420-35-0)
• EPA Substance Registry System: 3-(ETHYLTHIO)-1H-1,2,4-TRIAZOL-5-AMINE(51420-35-0)

Safety Data

• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 51420-35-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C4H8N4S/c1-2-9-4-6-3(5)7-8-4/h2H2,1H3,(H3,5,6,7,8)

Upstream product

• 16691-43-3 5-Amino-3-mercapto-1,2,4-triazole 
• 55198-87-3 cyano dithiocarbimidoic acid diethyl ester 
• 16691-43-3 3-amino-5-thioxo-1,2,4-triazole 

Downstream Products

• 1349163-14-9 7-(4-chlorophenyl)-2-(ethylthio)-5-methyl-N-phenyl-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide 
• 1349163-12-7 7-(4-ethylphenyl)-2-(ethylthio)-5-methyl-N-phenyl-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide 
• 3735-92-0 N,N,S-trimethyldithiocarbamate 
• 131023-10-4 methyl (3-ethylthio-1,2,4-triazol-5-yl)aminodithiocarbonate 
• 79742-00-0 3-Amino-5-ethylsulfanyl-[1,2,4]triazole-4-carboxylic acid methyl ester 

Relevant articles and documents

Synthesis and antiproliferative evaluation of novel 1,2,4-triazole derivatives incorporating benzisoselenazolone scaffold

A series of novel 1,2,4-triazole derivatives incorporating benzisoselenazolone scaffold were designed, synthesized and evaluated for their in vitro antiproliferative activities against human cancer cell lines SMMC-7721, Hela, A549, and normal cell lines L

On Triazoles. I. The reaction of N-Cyanocarbonimidodithioic Acid Diesters With Hydrazines

The reaction of N-cyanocarbonimidodithioic acid di(alkyl and aralkyl)esters with different alkyl-, aralkyl- and aryl hydrazines to yield 1-substituted-3-R-thio-5-amino-1H-1,2,4-triazoles (3) and 2-substituted-3-R-thio-5-amino-2H-1,2,4-triazoles (4) was studied.Isolation of the different types of isomeric pairs of 3 and 4 helped to prove the structure of products obtained which made possible correction of some confusion in the literature.The 3 (R = H) tautomeric structure of the non-substituted derivatives was supported by comparison of their uv and cmr spectra with those of the alkylated and aralkylated derivatives 3 and 4, respectively, again correcting confusion in literature.An hplc determination of the ratio of products 3 and 4 formed in the above reactions with different hydrazines made it possible to prove the mechanism of the reaction.