514214-66-5Relevant articles and documents
Total Synthesis of Pyrophen and Campyrones A-C
Reber, Keith P.,Burdge, Hannah E.
, p. 292 - 297 (2018)
The first total syntheses of the natural products pyrophen and campyrones A-C, isolated from the fungus Aspergillus Niger, have been achieved in six steps starting from commercially available N-Boc amino acids. Key steps in this sequence include a vinylog
Design, synthesis, antimicrobial, and DNA gyrase inhibitory properties of fluoroquinolone–dichloroacetic acid hybrids
Seliem, Israa A.,Panda, Siva S.,Girgis, Adel S.,Nagy, Yosra I.,George, Riham F.,Fayad, Walid,Fawzy, Nehmedo G.,Ibrahim, Tarek S.,Al-Mahmoudy, Amany M. M.,Sakhuja, Rajeev,Abdel-samii, Zakaria K. M.
, p. 248 - 259 (2019/11/14)
A series of new fluoroquinolone conjugates 8a–g and 9a–f were synthesized via benzotriazole-mediated synthetic approach with good yield and purity. Some of the synthesized analogs exhibited significant antibacterial properties against Escherichia coli and
A simple and versatile method to synthesize N-acyl-benzotriazoles
Laconde, Guillaume,Amblard, Muriel,Martinez, Jean
supporting information, p. 341 - 343 (2019/01/04)
An efficient method for the synthesis of N-acyl-benzotriazoles from a wide variety of protected amino acids, as well as from compounds frequently used in drug discovery such as biotin and N-Fmoc polyethylene glycol, has been developed. The reaction of car
