51478-04-7Relevant articles and documents
Syntheses of (14β,15β,16β,17α)- and (14β,15α,16α,17α)-1,3,5(10)-Estratriene-2,3,14,15, 16,17-hexaols, Possible Candidates for the Inagami-Tamura Endogenous Digitalis-like Factor, and Their Activity
Sakakibara, Masayuki,Uchida, Aki Ogawa
, p. 405 - 410 (2007/10/03)
Structures are proposed for the Inagami-Tamura endogenous digitalis-like factor (EDLF), and two possible candidates, (14β,15β,16β,17α)- and (14β,15α,16α,17α)-2,3,14,15,16,17-hexahydroxy-1,3,5(10)- estratrienes, were synthesized. Both compounds were potent in inducing a contractile response in isolated rat aorta and guinea pig left atrium.