515129-88-1Relevant articles and documents
A one-pot synthesis of 1-arylalka-1,3-diynes by sequential acetylene zipper and Sonogashira reactions
Balova, Irina A.,Morozkina, Svetlana N.,Knight, David W.,Vasilevsky, Sergei F.
, p. 107 - 109 (2003)
1,3-Diynes, formed in situ by base-induced acetylene zipper reactions, following anion quenching with water, undergo smooth Sonogashira-type couplings with functionalized aryl iodides, to give good overall yields of 1-arylalka-1,3-diynes.
"Acetylene zipper" reactions and Pd-Cu-catalyzed cross-coupling in the synthesis of vicinal 1,3-alkadiynylarylamines and aminopyridines
Balova,Morozkina,Sorokoumov,Vinogradova,Vasilevskii
, p. 1613 - 1617 (2007/10/03)
A preparative method was developed for vicinal-substituted 1,3-alkadiynylarylamines and aminopyridines involving a successive application of "acetylene zipper" reaction to synthesize 1,3-alkadiynes followed by Sonogashira reaction.
