515875-38-4

Basic information

• Product Name: 3-(2-furyl)-6-phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
• Synonyms: 3-(2-furyl)-6-phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
• CAS NO: 515875-38-4
• Molecular Formula: C13H8N4OS
• Molecular Weight: 268.29382
• Mol File: 515875-38-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(2-furyl)-6-phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-furyl)-6-phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole(515875-38-4)
• EPA Substance Registry System: 3-(2-furyl)-6-phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole(515875-38-4)

Safety Data

• Hazardous Substances Data: 515875-38-4(Hazardous Substances Data)

Upstream product

• 91468-61-0 potassium N'-(furan-2-carbonyl)-hydrazinecarbodithioate 
• 80809-38-7 4-amino-3-(2-furyl)-5-mercapto[4H]-1,2,4-triazole 
• 65-85-0 benzoic acid 

Relevant articles and documents

3. 6 - Disubstituted [1, 2, 4] triazolo [3, 4 - b] [1, 3, 4] thiadiazole compound and use thereof

The invention discloses 3,6-disubstituted[1,2,4]triazolyl[3,4-b][1,3,4]thiadiazole compounds represented by general formula (I), and pharmaceutically acceptable salts or pharmaceutically acceptable solvates thereof. The compounds can be used as a transpeptidase SrtA inhibitor of Staphylococcus aureus, Bacillus pyogenes, Bacillus anthracis, Streptococcus pneumoniae and other Gram-positive bacteria, and can be used to prepare drugs for treating pathogen infection diseases with the transpeptidase SrtA of the Gram-positive bacteria, such as Staphylococcus aureus, Bacillus pyogenes, Bacillus anthracis and Streptococcus pneumoniae as target. The compounds avoid selection pressure induced drug resistance of pathogens to a certain degree, and mitigate threat of continuous drug-resistant pathogens to the health of human.